摘要
目的探讨入院24h内重症急性胰腺炎转归的危险因素。方法自2000年1月至2003年12月我院收治的重症急性胰腺炎60例,按预后分为死亡组21例和生存组39例,回顾性分析入院24h内临床和实验室检查资料,并行Logistic回归分析。结果死亡组年龄为(66.6±16.1)岁,入院时呼吸频率为(29±9)次/min,24h尿量为(1062±815)ml,血肌酐为(190.6±120.1)μmol/L,动脉血氧分压为(58.5±17.3)mmHg,APACHEⅡ评分为19.3±7.5;而生存组分别为(52.4±13.1)岁,(20±2)次/min,(1648±575)ml,(94.4±56.0)μmol/L,(78.8±18.0)mmHg和9.1±2.0,两组比较差异有统计学意义(P<0.01),心率、血糖、血清白蛋白、血pH值、24h内通便与否差异亦有统计学意义(P<0.05),而平均动脉压、血尿淀粉酶、白细胞、红细胞压积、血小板、血脂、肝功能、电解质及男女比例无显著差异。经多因素Logistic回归分析发现年龄、动脉血氧分压、血清白蛋白与重症急性胰腺炎死亡相关。结论年龄、动脉血氧分压和血清白蛋白是重症急性胰腺炎死亡独立的危险因素。
Objective To investigate the risk factors of death in patients with severe acute pancreatitis within 21 hours after admission. Methods Sixty patients with severe acute pancreatitis admitted from Jan. 2000 to Dec. 2003 were divided into two groups , death group 21 cases and survival group 39 cases. Clinical and laboratory data within 24 hours after admission of those patients were analyzed retrospectively, and Logistic regression analysis was performed. Results The average age in death group was （66.6±16. 1）years,breath rate in admission （29±9） rain, urine volume within 24 hours（1062±815） ml,serum creatinine（190.6±120. 1）μmol/L, arterial pressure of O2（58. 5±17. 3） mm Hg, APACHE Ⅱ score 19.3±7.5;while correspondent data in survival group were （52.4± 13. 1） years,（20±2）/min, （1648±575） ml. （94.1±56. 0）μmol/L.（78.8±18.0） mm Hg and 9. 1±2.0,respectively. Significant differences were existed between two groups（P〈0. 01）. Marked differences were also found in heart rate. blood sugar, serum albumin, arterial pH and early defaecation within 24 hours after admission（P〈 0.05）. And mean arterial pressure, blood and urine amylase, white blood cell count, haematocrit, platelet count, blood cholesterol and triglycerol, liver function, electrolytes, gender proportion did not have significant differences between two groups. But multiple I.ogistic regression analysis showed that age, arterial pressure of O2 and albumin were associated with death. Conclusion The age. arterial pressure of O2 and serum albumin were tbe independent risk factors for evaluating the prognosis of severe acute pan creatitis.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2005年第8期454-457,共4页
Chinese Journal of Digestion
关键词
重症急性胰腺炎
疾病转归
血氧分压
白蛋白
Severe acute pancreatitis
Risk factors
Logistie regression analysis
