摘要
运用电子轰击离子化（ＥＩ）／傅立叶变换离子回旋共振（ＦＴＩＣＲ）质谱技术实现了喹诺酮类药物负离子质谱的测定，并对实验条件做了详细的探讨。通过七种药物的负离子质谱的研究，发现了一种极有规律性的裂解方式及这种裂解方式产生的、具有较高稳定性的特征负离子。
Electron impact(El)/Fourier transform ion cyclotron resonance(FTICR)mass spectrometry was developed to study the negative ion mass spectra of 7 quinolone drugs.One kind of the regular fragmentation pethway was found.The negative ions preduced by the pathway have high stability.The experimental conditions were diseussed in detail.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1995年第3期149-151,共3页
Journal of China Pharmaceutical University
关键词
喹诺酮类药物
负离子质谱
FTICR
抗生素
Quinolone drugs
Negative ion mass spectrometry
Fourier transform ion cyclotron resonance(FTICR)mass spectrometry
Electron impact(El)
