摘要
目的测定种植体周围炎患者龈沟液(GCF)中白细胞介素-8(IL-8)水平,探讨IL-8与种植体周围炎的关系。方法选择健康种植体和种植体周围炎患者各35例,测定种植体周GCF量并运用双抗体夹心酶联免疫吸附法检测GCF中IL-8总量及浓度;同时检测种植体周临床指标,包括菌斑指数、探诊深度、牙龈指数和松动度。结果种植体周围炎GCF量、IL-8总量和浓度均高于健康种植体(P<0·01);GCF量、IL-8总量与临床指标之间有正相关关系(P<0·01)。结论种植体周围GCF量及GCF中IL-8水平的变化与种植体周围炎的发生有关,临床检测GCF中IL-8水平可作为诊断种植体周围炎的客观指标之一。
Objective Gingival crevicular fluid （GCF） analysis of various inflammatory mediators has been investigated as a means of providing objective criteria of peri-implant tissue health. In this report, the crevicular fluid levels of interleukin-8 （ IL-8 ）,GCF volume and clinical parameters were studied. Methods GCF was sampled from 35 healthy and 35 inflamed sites of implantation patients. IL-8 levels were analysed using ABC-ELISA. Clinical parameters were measured, and data analysis was performed using the software package SPSS10.0. Results Significant difference was observed between healthy implant sites and peri-implantitis sites. GCF volume was positively correlated with PD, PI, GI and MOB. The total amount of IL-8 was positively correlated with PD and GI. Conclusion Tuis investigation suggested that GCF volume and IL-8 eytokine may be of value as a diagnestie and prognostic marker for peri-implanfitis.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2005年第4期292-294,共3页
West China Journal of Stomatology
