摘要
对８２例乳腺癌和３５例乳腺良性病变（ＭＢＬ）组织中ＥＲ、ＰＲ、ＰＲＬ、６ＰＧＤＨ和ＩＣＤＨ活性进行组化检测。结果提示：乳腺癌丧失其激素依赖性高于ＭＢＬ；６ＰＧＤＨ和／或ＩＣＤＨ阳性的乳腺纤维囊性增生病可能为癌前病变；乳腺癌中ＰＲ，６ＰＧＤＨ，ＩＣＤＨ的合成受雌激素诱导，可作为乳腺癌功能性ＥＲ的标志物，ＰＲＬ与ＥＲ在乳腺癌中可能起相互促进作用。
Distribitions of ER, PR,PRL,6PGDH,ICDH in BC and MBL and their relationships in BCwere studied by histochemical methods.In addition,the biological significances of assaying ER,PR,PRL,6PGDH and ICDH in BC and MBL were discussed.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1995年第2期82-84,共3页
Cancer Research on Prevention and Treatment
