摘要
哺乳动物的下丘脑、垂体和卵巢分泌的激素在功能上相互作用,构成一个完整的神经内分泌生殖调节体系,即下丘脑垂体卵巢轴,它在生殖活动中起着主要的调节作用。下丘脑中分布的GnRH神经元可以分泌GnRH,GnRH调节垂体中促性腺激素细胞分泌促性腺激素FSH和LH,促性腺激素作用于卵巢受体,引起雌激素和孕酮分泌并影响生殖活动。从组织学角度上研究,下丘脑垂体卵巢轴中的结构,如GnRH神经元、促性腺激素细胞、卵泡随周期性变化而呈现出不同的形态结构和分泌特点。因此,对以上各种细胞的研究是探讨其所分泌激素的基础,而下丘脑垂体卵巢轴中的各种激素的研究则是了解和控制动物繁殖机能的关键。
In the endocrinology of mammalian, the hormones secreted by hypothalamus,Pituitary and Ovary work together to form a whole nervous incretion system.This system is called Hypothalamus-Pituitary-Ovary axis ,which has important place in animal'reproduction. GnRH neuron in hypothalamus can secrete GnRH,which can promote gonadotrophs in pituitary to secrete.Then FSH,LH reach ovary,and combine with receptors which can arouse reproduction. From the side of histology,the important parts of Hypothalamus-Pituitary-Ovary axis are GnRH neuron,gonadotroph and follicular.Their function and morphology are changed with the season.So the histological study of axis is the base of studying hormone,which is the key to understand and control mammalian reproduction.
出处
《动物医学进展》
CSCD
2005年第7期8-11,共4页
Progress In Veterinary Medicine
基金
山东省教育厅资助项目
