摘要
目的 观察舒降之、低分子肝素、氯比格雷联合治疗不稳定型心绞痛。方法 60 例不稳定型心绞痛病人分为两组—观察组和对照组。观察组给予舒降之、低分子肝素、氯比格雷联合治疗,对照组用硝酸甘油静滴,两组均辅以硝酸酯类、钙拮抗剂、β受体阻滞剂、ACEI,用药2 周,治疗前及治疗的第1 周均作心电图检查,结束时再作心电图。结果 观察组总有效率93%,对照组总有效率60%。两组总有效率经统计学处理P<0 .01,有显著差异,说明观察组的疗效优于对照组。结论 舒降之、低分子肝素、氯比格雷联合治疗不稳定型心绞痛疗效肯定,在改善症状、心电图及降脂祛斑、抗血栓形成方面均起到了积极作用,减缓了该病向急性心肌梗死方面发展。
Objective To evaluate the clinical effect of simvastation in combination with low molecular weight heparin and clopisogrel sulfate in treating patients with unstable angina.Methods Sixty patients with unstable angina were randomly divided into two groups,group A (n=30) as the observation group was prescribed with simvastatin in combination with low molecular weight heparin and clopisogrel sulfate, group B(n=30) as the control group was prescribed with nitroglycerin for use intravenously.Both two groups were all treated with nitrates,calcium antagonists,β-blockers and ACEI for two weeks.ECG was taken before treatment and after treatment in one week and two weeks.Results The total effective rate in observation group (93%) was significantly higher than that in control group (60%,P<0.01), which indicated that patients in observation group is more effective than that in control group.Conclusion Treatment with simvastation in combination with low molecular weight heparin and clopisogrel sulfate is effective in relieving symptoms, improving ECG alterations, dissolving the plaques and combating thrombosis, which prevented patients with unstable angina from developing acute myocardial infarction (AMI) and sudden death.
出处
《临床医学》
CAS
2005年第5期6-7,共2页
Clinical Medicine