摘要
应用高效液相色谱技术，对足月正常分娩儿（１１例）、胎儿窘迫儿（３０例）的脐动脉血浆、及足月后羊水（３６例）中儿茶酚胺水平进行测定。结果表明：胎儿窘迫时，儿茶酚胺水平增高，以去甲肾上腺素（ＮＥ）、肾上腺素（Ｅ）为主，其增高的程度与新生儿窒息发生有关，并与Ａｐｇａｒ评分呈负相关。相关系数分别为ｒ＿（ＮＥ）＝－０．６３９（Ｐ＜０．０１），ｒ＿Ｅ＝－０．４５９（Ｐ＜０．０５）。儿茶酚胺增加是胎儿缺氧的早期表现。因此，监测胎儿儿茶酚胺水平，可作为早期诊断胎儿窘迫的一个指标。
Catecholamine(CA) levels of umbilical artervwere detennined by high perfonnance liquidchromatography(HPLC) in 11 normal term deliverybabies and 30 infants with intrauterine fetal distress.and CA in their amniotic fluid which was collectedafter delivery was also determined.Results Showedthat CA levels,mainly norepinephrine(NE)andepinephrine(E),in umbilical artery of distressedbabies were significantly higher than that of nonnalinfants.The degree of increase was related to the oc-currence of neonatal asphyxia,and was negatively cor-related with Apgar score. The correlation coefficiencybetween NE, E and Apgar score was r_(NE)=-0.639,P< 0.01, and r_E=-0.459,P<0.05,respectively.Theincreasc of CA level was an early signal of fetalhypoxia. We believe that CA level in umblical arteryand amniotic fiuid was a good index for earlydiagnosis of fetal distress.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1994年第4期210-212,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
儿茶酚胺类
胎儿窘迫症
脐动脉
羊水
Catecholamines
Fetal distressUmbilical artery
Amniotic fluid
