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嵌合异硫氰酸罗丹明B核壳荧光纳米颗粒制备的新方法研究 被引量:12

New Method for Preparing Core-shell Fluorescent Nanoparticles Doped with Rhodamine B Isothiocyanate
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摘要 In this article, the preparation of core-shell fluorescent dye nanoparticles doped with rhodamine B isothiocyanate by using novel method is reported, which involves synchronous hydrolysis of tetraethoxysilane(TEOS) in water in oil microemulsion with the combination of N-(β-amimoethyl)-γ-amino propyltriethoxy-silane(AEAPS) and rhodamine B isothiocyanate(TRITC). This method conquers the disadvantages of traditional preparation method about organic dye doped core-shell nanoparticles such as the leakage of fluorescent dyes and the low encapsulation efficiency of fluorescent dyes. The fluorescent nanoparticle prepared by using the novel method have the advantages such as high fluorescence and good fluorescent stability, which are hopeful to be applied in the field of biological labelling. In this article, the preparation of core-shell fluorescent dye nanoparticles doped with rhodamine B isothiocyanate by using novel method is reported, which involves synchronous hydrolysis of tetraethoxysilane(TEOS) in water in oil microemulsion with the combination of N-(β-amimoethyl)-γ-amino propyltriethoxy-silane(AEAPS) and rhodamine B isothiocyanate(TRITC). This method conquers the disadvantages of traditional preparation method about organic dye doped core-shell nanoparticles such as the leakage of fluorescent dyes and the low encapsulation efficiency of fluorescent dyes. The fluorescent nanoparticle prepared by using the novel method have the advantages such as high fluorescence and good fluorescent stability, which are hopeful to be applied in the field of biological labelling.
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2005年第3期446-448,共3页 Chemical Journal of Chinese Universities
基金 国家自然科学基金重点项目 (批准号 :2 0 13 5 0 10 ) 国家重点基础研究发展规划项目 (批准号 :2 0 0 2 CB5 13 10 0 -10 ) 教育部科学技术研究项目 (批准号 :0 3 181) 国家科技计划项目 (批准号 :2 0 0 3 BA 3 10 A16) 国家自然科学基金 (批准号 :2 0 40 5 0 0 5
关键词 异硫氰酸罗丹明B(TRITC) 油包水微乳液 同步水解 核壳荧光纳米颗粒 TRITC Water in oil microemulsion Synchronous hydrolysis Cort-shell fluorescent nanoparticle
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