摘要
以免疫荧光双标记单克隆抗体及流式细胞仪检测外周血淋巴细胞亚群 ,在 2型糖尿病患者尤其是非肥胖型患者中 ,外周血CD3 + CD8+ 阳性细胞数显著低于健康对照组 ,而CD4/CD8比值增高。 2型糖尿病患者特别是非肥胖型可能存在明显的细胞免疫功能异常。
Lymphocyte subgroup in peripheral blood was assayed with immunofluorescent double labeled monoclonal antibodies and flow cytometry. The number of CD-3CD-8 positive cells was significantly decreased in diabetics II especially in non-obese people than that in health controls, and CD 4/CD 8 ratio in diabetic II group raised. Diabetic II especially non-obese ones might have significant immune dysfunction.
出处
《微生物学杂志》
CAS
CSCD
2005年第1期101-103,共3页
Journal of Microbiology
关键词
糖尿病
非胰岛素依赖型
T淋巴细胞
diabetes mellitus
non-insulin-dependent
T-lymphocytes
