摘要
目的观察温阳益气、散结泄水法治疗肺癌胸水的疗效及与胸腔灌注化疗的协同作用。方法选取肺癌胸水肺气虚和气阴两虚证住院患者50例,分层后随机分为具温阳益气、散结泄水治法的桂芪葶百汤联合胸腔灌注化疗组(治疗组)和单纯胸腔灌注化疗组(对照组)各25例,从胸水缓解、原发灶变化、生活质量变化、不良反应等方面进行临床观察。结果对胸水的疗效,治疗组优于对照组(P<0.05);对原发灶的有效率,两组比较无显著性差异(P>0.05);生活质量(卡氏评分),治疗组优于对照组(P<0.01);减轻消化道反应,治疗组优于对照组(P<0.01)。结论温阳益气、散结泄水法治疗肺气虚和气阴两虚型肺癌胸水有较好疗效,与胸腔灌注化疗联用有协同作用,疗效明显优于单纯胸腔灌注化疗。
Objective To observe the curative effects of traditional Chinese medicine treatment method of warming Yang and invigorating Qi, dispersing mass and expelling fluid retention combined with the chemotherapy through the perfusion of the chest on the pleural effusion secondary to lung cancer. Methods 50 pleural effusion secondary to lung cancer patients with the syndrome of Qi deficiency of the lung (SQDL) and the syndrome of both Qi and Yin deficiency of the lung (SQYDL) were selected, and divided randomly into the treatment group (treated with the Guiqitingbai decoction that have the effects of warming Yang and invigorating Qi, dispersing mass and expelling fluid retention combined with chemotherapy through the perfusion of the chest) and the control group (treated with single chemotherapy through the perfusion of the chest) after stratification, with each group having 25 cases. The clinical curative effects were observed and compared. Results Based on the clinical observation on the effects of pleural effusion, the treatment group had a better curative effect than the control group (P<0.05). There was no difference between the treatment group and the control group in the effective rate of curing the primary focus of pleural effusion secondary to lung cancer (P>0.05). Evaluated by the scoring method of Karnofsky. The quality of life of the treatment group was better than that of the control group (P<0.05). Alleviation of the toxicity and side-effects of chemotherapy on the digestive, the treatment group was better than that of the control group (P<0.05). Conclusion The traditional Chinese medicine treatment method of warming Yang and invigorating Qi, dispersing mass and expelling fluid retention has a satisfactory curative effect on the pleural effusion secondary to lung cancer with SQDL and SQYDL. It has cooperation when combined with chemotherapy through the perfusion of the chest. The curative effects of these two treatment method combined is better than that of single chemotherapy through the perfusion of the c
出处
《中国中医药信息杂志》
CAS
CSCD
2005年第3期12-13,共2页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家中医药管理局基金资助(02-03JP30)
湖南省自然科学基金资助(01JJ2037)
关键词
肺癌胸水
温阳益气
散结泄水
桂芪葶百汤
胸腔灌注化疗
pleural effusion secondary to lung cancer
warming Yang and invigorating Qi
dispersing mass and expelling fluid retention
Guiqitingbai decoction
chemotherapy through the perfusion of the chest
