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国产和进口氧氟沙星治疗伤寒和副伤寒的疗效比较 被引量:7

Comparison of therapeutic effects between domestic and imported ofloxacin in treating typhoid and paratyphoid fever
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摘要 伤寒、副伤寒共54例,以国产氧氟沙星治疗26例(男性13例,女性13例;年龄26±s 7a),用进口氧氟沙星治疗28例(男性19例,女性9例;年龄28±9a)。剂量均为300mg, po, bid。疗程7d。结果:2组临床有效率均为100%,细菌阴转率分别为96%和100%。随访2mo均未见复发病例。提示2药治疗伤寒、副伤寒的疗效相同(P>0.05)。 A controlled study of therapeutic effects between domestic and imported ofloxacin in 26 patients(M 13, F 13; age 26 ± 7 a) and 28 patients(M 19, F 9; age 28 ± 9a) with typhoid and paratyphoid fever respectively was done. The dosage were all 300 mg, bid, po, for 7 d. The results showed that the total response rate were all 100%, and the bacterial eradication rate were 96% and 100% respectivelv The therapeutic effects between the two drugs were not statistically different(P>0.05).
出处 《新药与临床》 CSCD 北大核心 1993年第5期287-288,共2页
关键词 氧氟沙星 伤寒 药理学 ofloxacin typhoid paratyphoid fevers drug evaluation
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  • 1H. L. DuPont. Use of quinolones in the treatment of gastrointestinal infections[J] 1991,European Journal of Clinical Microbiology & Infectious Diseases(4):325~329 被引量:1
  • 2方鹤松,张振华,路文彬,赵锦铭,刘瑞琴,孙君莉,马晓红,张志良,关德华,陈庆武,赵翠兰,邓杰,于福寿,徐江,丁韵珍,孙吉萍,于云.北京市小儿急性腹泻病病原学监测[J].北京医学,1991,13(4):193-196. 被引量:6

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