摘要
目的建立尿通片中丹参酮ⅡA的含量测定方法。方法采用薄层扫描法测定尿通片中丹参酮ⅡA的含量,以苯-醋酸乙酯(19∶1)为展开剂,λs=470nm,λR=620nm,SX=3。结果丹参酮ⅡA在0.44μg～2.20μg之间线性关系良好,相关系数r=0.9993(n=5);平均回收率99.08%,RSD=3.29%。结论该方法简便、快速、重现性好,可用于该制剂及丹参药材的含量测定及质量控制。
Objective To establish a quality control method for tanshinone ⅡA in Niaotong Tablets.Methods The content of tanshinone ⅡA was determined by TLC-scanning method. Benzene-ethyl acetate(19 ∶1) was used as the developer, λs = 470nm,λR = 620nm,SX=3.Results A linearity was obtained from 0.44μg to 2.20 μg of tanshinone ⅡA in Niaotong Tablets (r=0.9993,n=5);the average recovery rate was 98.08 %,RSD=3.29 %.Conclusion This method is simple, sensitive and reproducible for the determination of tanshinone ⅡA in Niaotong Tablets and Radix Salviae Miltiorrhizae.
出处
《中药新药与临床药理》
CAS
CSCD
2004年第6期419-420,共2页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
尿通片
丹参酮ⅡA
薄层扫描法
含量测定
Niaotong Tablets
Tanshinone ⅡA
TLC-scanning method
Content determination
