摘要
目的 介绍阳性药对照临床试验中3种有效性评价的可信区间方法,并将其与传统的假设检验方法进行比较。方法与结果 用假设检验和可信区间方法分别对3个阳性药对照试验进行了计算与分析在3种情况下均显示了可信区间方法的适用性。结论 在阳性药对照临床试验中,传统假设检验方法具有明显的局限性,建议结合可信区间方法使用。
Objective To introduce confidence interval (CI) method for threecondition in active controlled clinical trial , and compare it with hypothesis testmethod. Methods and Results Assess efficacy in three active controlled clinical trialusing hypothesis test and CI method. CI method can be used to assess the efficacyof treatment is showed in three condition. Conclusion In active controlled clinicaltrial , the used method was limited. It will be more clear by combine CI method.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2004年第5期389-391,共3页
The Chinese Journal of Clinical Pharmacology
关键词
阳性对照
假设检验
可信区间
active control
hypothesis test
confidence interval
