摘要
目的 探讨冠状动脉粥样硬化性心脏病 (CHD)患者血清胰岛素与血压及血脂间的关系。方法 对 57例患者 (CHD组 )和 2 2例健康者 (对照组 ) ,进行胰岛素、血压及血脂测定。结果 CHD组的胰岛素、血压、甘油三脂 (TG)、低密度脂蛋白 (LDL)均高于对照组(P <0 .0 5)。CHD组中胰岛素水平与血压及TG、LDH成正相关 ;单纯冠心病组与CHD并发原发性高血压组间胰岛素、TG、LDL无显著性差异 (P >0 .0 5)。结论 CHD患者存在胰岛素抵抗 (IR)高胰岛素血症。高胰岛素血症 ,血压及血脂异常与IR相互影响 ,共同参与CHD的发生和发展。
Objective To study the relationship between the serum insulin and blood pressure and plasma lipid in patient with coronary atherosclerotic heart disease (CAHD). Methods Serum insulin, blood pressure and plasma lipid were assay in 57 CAHD patients (CAHD group) and 22 healthy persons (control group). Results The serum insulin, blood pressure, triglycerides (TG) and low density lipoprotein (LDL) in CAHD group were higher than in control group (P<0.05). In CAHD group, the insulin level was correlated to the blood pressure, TG and LDH positively. And the difference of the insulin, TG and LDL were insignificant between patients with CAHD only and CAHD patients combined with hyperpietic (P>0.05). Conclusions Insulin resistance (IR) existed in patients with CAHD. abnormal blood pressure and abnormal plasma lipid. The IR, abnormal blood pressure and blood lipid influenced each other, and they influenced the development of CAHD together.
出处
《实用全科医学》
2004年第6期504-505,共2页
Applied Journal Of General Practice
关键词
冠心病
血压
血脂
高胰岛素血症
胰岛素抵抗
Coronary atherosclerotic heart disease
Insulin
Blood pressure
Plasma lipid
