摘要
目的 测定养阴镇静片中阿魏酸的含量。方法 用高效液相色谱法 ,色谱柱为DiscoveryC18柱 ,流动相为乙腈 0 .5 %冰醋酸 ( 2 0∶80 )。结果 阿魏酸浓度线性范围为 0 .0 14 4 4～ 0 .10 83mg/mL ,r =0 .9999,平均回收率为 97.13% (n =5 ) ,RSD为2 .0 4 % (n =5 ) .结论 方法简便、准确、重复性好 。
OBJECTIVE To establish a method for determination the content of ferulic acid in Yangyin Zhenjing tablet by HPLC. METHOD Discovery C 18 was used as a stationary phase, acetontrile 0.5% acetic acid solution (20∶80) was used as the mobile phase. The UV VIS dector was set at 335nm.RESULTS The assay was linear in the range of 0.01444～0.1083mg/mL( r =0.9999). The average recovery of ferulic acid was 97.13%( RSD =2.0%).CONCLUSION The method is simple and accurate with a good reproducibility, which can be used as quantitative method for this preparation.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2003年第6期501-502,共2页
Chinese Journal of Modern Applied Pharmacy
关键词
养阴镇静片
阿魏酸
含量测定
Yangyin Zhenjing tablet
ferulic acid
determination
