摘要
目的 探讨白癜风的病因并为皮质类固醇激素及免疫调节剂治疗白癜风提供理论根据。方法 采用间接免疫荧光技术检测 5 8例白癜风患者血清抗黑素细胞IgG抗体 ,选择 17例抗黑素细胞IgG抗体阳性的进展期患者给予皮质类固醇激素及免疫调节剂治疗 ,然后再检测该抗体。结果 11例治疗有效的进展期白癜风患者抗体阳性率治疗后明显降低。结论 白癜风患者血清中抗黑素细胞IgG抗体水平随着治疗后病情的好转而降低 ,表明白癜风与自身免疫密切相关 。
Objective To study the etiological of vitiligo and furnish theoretical basis for corticosteroid and immunoregulator to treat viˉtiligo.Methods Sera of58vitiligo patients were tested melanocyte IgG antibody with indirect immunofluorescence technique.17of58vitiligo patients of progressive stage with the positive reaction to melanocyte antibodies were treated with corticosteroid and immunoregulator,and again antibodies were tested after treatment.Results 11of17progressive patients showed effective to treatment,and their antibody positive rate were then marked dropped after treatment.Conclusion The change of melanocyte IgG antibody of vitiligo patients along with improvement of the disˉease after treatment furnished evidence that vitiligo has a close link with autoimmune.Corticosteroid and immunoregulator to treat progressive viˉtiligo achieve good results.
出处
《宁夏医学杂志》
CAS
2004年第7期387-389,共3页
Ningxia Medical Journal
基金
20 0 3年宁夏教育厅科研基金项目 (编号 2 1 1 )
