摘要
血管生成素是近年研究较多的血管生成因子,在血管生成和稳定性的维持中起着重要作用。其中,子宫和卵巢内以血管生成素-1和血管生成素-2的存在为主。目前妇产科领域对这两者的研究发现其可促进子宫内膜的增生和修复,同时影响卵泡的发育和成熟、排卵及黄体的生成和发育。血管生成素-1和血管生成素-2的异常表达与胎儿生长受限、子宫内膜异位症等疾病的发病有关。
Angiopoietin is an important angiogenic factor.It plays a crucial role in formation and stability maintenance of blood vessels.Angiopoietin-1(Ang-1) and Angiopoietin-2(Ang-2) are expressed in uterus and ovary mainly.The research on them in gynecology and obstetrics shown that they can promote proliferation and repair of endometrium,and may affect follicle development,maturation,ovulation and formation and development of corpus luteum.The abnormal expression of them may be associated with development of fetal growth restriction(FGR),endometriosis and so on.
出处
《中国妇幼健康研究》
2007年第6期538-540,共3页
Chinese Journal of Woman and Child Health Research
