摘要
痛风是由于嘌呤代谢紊乱及(或)尿酸排泄减少所致的高尿酸血症引起的急、慢性炎症和组织损伤,主要表现为痛风性关节炎、痛风肾和痛风石的一种代谢性风湿病。阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea,OSA)属于睡眠呼吸障碍类疾病,是呼吸内科、心脑血管、肾脏系统类等疾病发病的危险因素。目前,有研究发现OSA可影响体内血尿酸水平,导致痛风发病升高。本文就OSA的流行病学特点与痛风发病关系的研究进展进行综述。
Gout is an acute,chronic inflammation and tissue damage caused by hyperuricemia due to purine metabolic disorders and/or reduced uric acid excretion.Obstructive sleep apnea(OSA)is a sleep disordered breathing disease,which is a risk factor for respiratory medicine,cardiovascular and cerebrovascular diseases,kidney system and other diseases.At present,studies have found that OSA can affect the level of uric acid,resulting in increased incidence of gout.This paper reviews the research progress on the relationship between the epidemiological characteristics of OSA and the incidence of gout.
作者
陈建春
郭以川
周攀
郑武燕
CHEN Jian-chun;GUO Yi-chuan;ZHOU Pan;ZHENG Wu-yan(Chengdu Rheumatism Hospital,Chengdu,Sichuan 610072)
出处
《智慧健康》
2020年第32期51-52,55,共3页
Smart Healthcare
