摘要
目的:研究顶花板凳果Pachysandra terminalis Sied.et Zucc.中的化学成分。方法:采用硅胶、Sephadex LH-20葡聚糖凝胶、反相ODS C_(18)、半制备液相等色谱技术分离纯化,1D/2D-NMR、MS、IR等波谱学技术解析结构。结果:从顶花板凳果中共分离得到5个化合物,分别鉴定为:顶花板凳果素D(1)、aurantiamide acetate(2)、(+)-(7S,8R,8′R)-异落叶松脂酚(3)、cornilkone B(4)、L-焦谷氨酸甲酯(5)。结论:其中,化合物1为新化合物,化合物2~5为首次从该植物中分离得到。
Objective:To study the chemical constituents of Pachysandra terminalis.Methods:The chemical components were isolated and purified by silica gel,Sephadex LH-20,ODS C_(18) gel and semi preparative-HPLC chromatographic techniques,the structures were identified by 1D/2D-NMR,MS and IR spectral data analysis.Results:Five compounds were isolated from Pachysandra terminalis and identified as pactermine D(1),aurantiamide acetate(2),(+)-(7S,8R,8′R)-isolapsinol(3),cornilkone B(4),L-pyroglutamic acid methyl ester(5),respectively.Conclusion:Among them,compound 1 is a new compound,compounds 2 to 5 are isolated from Pachysandra terminalis for the first time.
作者
丁超
孙玉
王冯瑞
姜祎
张化为
张东东
宋小妹
DING Chao;SUN Yu;WANG Feng-rui;JIANG Yi;ZHANG Hua-wei;ZHANG Dong-dong;SONG Xiao-mei(College of Pharmacy,Shaanxi University of Chinese Medicine,Xianyang 712046,China)
出处
《中药材》
CAS
北大核心
2022年第7期1606-1609,共4页
Journal of Chinese Medicinal Materials
基金
国家自然科学基金项目(82104368)
陕西省科技厅自然科学基础研究计划项目(2021JQ-744)
陕西中医药大学创新团队项目(2019-YL12)
陕西中医药大学研究生创新项目(2021CX06)
关键词
顶花板凳果
化学成分
生物碱
顶花板凳果素D
Pachysandra terminalis Sieb.et Zucc.
Chemical constitutes
Alkaloids
Pactermine D
