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司库奇尤单抗治疗儿童寻常型银屑病1例并文献复习

Treatment of Vulgaris Psoriasis in Children with Secukinumab: Case Report and Literature Review
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摘要 患者女,6岁3个月,全身斑块、鳞屑伴痒1年。皮肤科情况:躯干、四肢、头部可见散在红斑、斑块,表面附着鳞屑。在排除肝炎、结核的基础上,经知情同意后,给予司库奇尤单抗标准治疗方案:在第0、1、2、3周进行皮下注射司库奇尤单抗150 mg,1次/周,共4次,在第1周达到PASI 75,第2周达到PASI 100,随访至今未见明显复发及不良反应。 A 6-year-old girl presented with patches and scales for one year.Dermatological examination showed that erythema and patches scattered on trunk,extremities,head with attached scales.After excluding hepatitis and tuberculosis,the patient was given the standard secukinumab treatment after signing informed consent.The dose was 150 mg subcutaneously once a week at the first four week.The PASI achieved to 75%at week 1 and 100%at week 2.There was no recurrence and adverse events during follow-up to date.
作者 宋运成 甘林权 杨东梅 黄姿婵 杨猛 SONG Yuncheng;GAN Linquan;YANG Dongmei;HUANG Zichan;YANG Meng(Department of Dermatology,the Third Affiliated Hospital of Guangxi Medical University,Nanning 530000,China)
出处 《皮肤科学通报》 2022年第4期374-376,共3页 Dermatology Bulletin
关键词 司库奇尤单抗 儿童银屑病 生物制剂 抗IL-17A Secukinumab Psoriasis in children Biologics Anti-IL17A
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