摘要
银屑病是一种常见的慢性、炎性皮肤病,临床表现为红斑或斑块伴有银白色鳞屑,发病与遗传、环境、免疫等因素相关。银屑病在儿童并不少见,诊断通常基于临床,需与特应性皮炎、苔藓样糠疹、毛发红糠疹等疾病鉴别。对于轻度银屑病应用局部外用药治疗即可控制病情,对于中重度的常需考虑光疗和系统治疗。近年来,国内外已批准部分生物制剂用于治疗儿童银屑病,为儿童银屑病的治疗提供了新的方法。本文就儿童银屑病的诊疗进展进行了综述。
Psoriasis is a chronic inflammatory skin disease which presents as scaly erythematous or plaques.The causes of psoriasis include genetic iheritance,environment,immune and other factors.Psoriasis is not uncommon in children.Its diagnosis is usually based on clinical signs and characteristics of the lesions.It should be differentiated from atopic dermatitis,pityriasis lichenoides and pityriasis rubra pilaris.The mild psoriasis can be controlled by topical treatment,but moderate or severe psoriasis need to consider phototherapy and systemic treatment.In recent years,some biological agents have been approved for pediatric psoriasis at home and abroad,which provide new methods for the treatment of children psoriasis.This article reviews the progress in the diagnosis and treatment of pediatric psoriasis.
作者
张振华
王召阳
徐子刚
ZHANG Zhenhua;WANG Zhaoyang;XU Zigang(Department of Dermatology,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China)
出处
《皮肤科学通报》
2022年第2期115-120,M0004,共7页
Dermatology Bulletin
基金
北京市自然科学基金资助项目(7212037)。
关键词
儿童
银屑病
生物制剂
诊断
治疗
Children
Psoriasis
Biological agents
Diagnosis
Treatment
