摘要
生存素(survivin)是凋亡抑制蛋白家族的新成员,具有肿瘤特异性,只表达于肿瘤和胚胎组织,且与肿瘤细胞的分化增殖及浸润转移密切相关。本文综述了Survivin的生物学特性,并着重阐述survivin与胶质瘤的关系及其在胶质瘤诊断和治疗中的新进展。
Survivin is a new member of inhibitor of apoptosis,it only expresses in tumor tissue and human embryonic development tissue,and high specificity in cancer tissue,which is closely bound up with tumor cell division,proliferation and correlation metathesis.The paper reviews the new advance of survivin in the biological behaviors and its correlation with glioma diagnosis and therapy.
出处
《内蒙古医科大学学报》
2008年第S1期640-643,共4页
Journal of Inner Mongolia Medical University
基金
内蒙古自治区自然科学基金项目(200408020902)
内蒙古医学院附属医院重大项目(200405)