以传统发酵乳制品中分离出的5株优良的乳杆菌为研究对象,对其在口腔中的存活率、聚合物和恶臭味的产生情况、产酸能力、抗生素敏感性、以及对变异链球菌生物膜形成的抑制作用进行评估,并探究其在预防龋齿方面的潜在应用价值。最终筛选出...以传统发酵乳制品中分离出的5株优良的乳杆菌为研究对象,对其在口腔中的存活率、聚合物和恶臭味的产生情况、产酸能力、抗生素敏感性、以及对变异链球菌生物膜形成的抑制作用进行评估,并探究其在预防龋齿方面的潜在应用价值。最终筛选出1株具有预防龋齿功能的植物乳杆菌CX013(Lactobacillus plantarum CX013)。该菌具有较好的口腔环境耐受力存活率值高达77.5%,可以形成聚集体具有较好的口腔定植能力,不产生恶臭味,有较强的抑制变异链球菌生物膜形成的能力,消除率可达53.75%,具有预防龋齿的潜力。展开更多
Background Decayed teeth are harmful to children＇s growth and development and can severely jeopardize their health. This study was set out to investigate and analyze the prevalence of dental caries in preschool child...Background Decayed teeth are harmful to children＇s growth and development and can severely jeopardize their health. This study was set out to investigate and analyze the prevalence of dental caries in preschool children in Shanghe County in Shandong Province, China, and provide new insights into potential prevention and treatment strategies. Methods Based on the random sampling method, we performed dental examinations of children aged 2 to 6 years in kindergartens of Shanghe County. The prevalence of caries, the average number of decayed teeth per capita as well as the constituent rates of decayed, missing and filled teeth were determined retrospectively. SPSS software was used for data analysis. Results Dental caries were found in 1088 out of 2052 children from 56 kindergartens. The total number of decayed teeth was 4487 with a prevalence of 53.02%. The average number of decayed teeth per capita was 2.187, and the filling rate was 0.29%. There was no statistical difference in the prevalence of caries between boys and girls though there were significant differences between different age groups. The prevalence of decayed teeth as well as the mean number of decayed teeth infected per capita increased with age. In addition, urban children had a higher prevalence than those from rural areas （P 〈0.01）. Conclusions The prevalence of decayed caries among kindergarten children in Shanghe County was high, suggesting that more emphasis should be put on improving oral health education with priority given to prevention. Further efforts should be made to increase the decayed caries filling rate.展开更多
AIM: To systematically review the literature on the efficacy of noninvasive methods of arresting the progression of non-cavitated occlusal carious lesions in dentin.METHODS: The Medline/Pub Med,LILACS,Sci ELO and Scop...AIM: To systematically review the literature on the efficacy of noninvasive methods of arresting the progression of non-cavitated occlusal carious lesions in dentin.METHODS: The Medline/Pub Med,LILACS,Sci ELO and Scopus databases were searched to identify relevant publications through to November 2013.Only clinical trials evaluating the ability of noninvasive methods to arrest the progression of occlusal non-cavitated carious lesions in dentin were included.Screening,data extraction and quality assessment were conducted independently and in duplicate.RESULTS: Of 167 citations identified,nine full text articles were screened and five were included in the analysis.All papers reported on occlusal fissure sealing using a self-curing glass ionomer(n = 1) or resin-based(n = 4) sealant.Only the use of resin-based sealant to obliterate occlusal fissures arrested the progression of non-cavitated occlusal carious lesions in dentin.CONCLUSION: Occlusal fissure sealing with a resin-based sealant may arrest the progression of non-cavitated occlusal dentinal caries.Further clinical trials with longer follow-up times should be performed to increase scientific evidence.展开更多
文摘以传统发酵乳制品中分离出的5株优良的乳杆菌为研究对象,对其在口腔中的存活率、聚合物和恶臭味的产生情况、产酸能力、抗生素敏感性、以及对变异链球菌生物膜形成的抑制作用进行评估,并探究其在预防龋齿方面的潜在应用价值。最终筛选出1株具有预防龋齿功能的植物乳杆菌CX013(Lactobacillus plantarum CX013)。该菌具有较好的口腔环境耐受力存活率值高达77.5%,可以形成聚集体具有较好的口腔定植能力,不产生恶臭味,有较强的抑制变异链球菌生物膜形成的能力,消除率可达53.75%,具有预防龋齿的潜力。
文摘Background Decayed teeth are harmful to children＇s growth and development and can severely jeopardize their health. This study was set out to investigate and analyze the prevalence of dental caries in preschool children in Shanghe County in Shandong Province, China, and provide new insights into potential prevention and treatment strategies. Methods Based on the random sampling method, we performed dental examinations of children aged 2 to 6 years in kindergartens of Shanghe County. The prevalence of caries, the average number of decayed teeth per capita as well as the constituent rates of decayed, missing and filled teeth were determined retrospectively. SPSS software was used for data analysis. Results Dental caries were found in 1088 out of 2052 children from 56 kindergartens. The total number of decayed teeth was 4487 with a prevalence of 53.02%. The average number of decayed teeth per capita was 2.187, and the filling rate was 0.29%. There was no statistical difference in the prevalence of caries between boys and girls though there were significant differences between different age groups. The prevalence of decayed teeth as well as the mean number of decayed teeth infected per capita increased with age. In addition, urban children had a higher prevalence than those from rural areas （P 〈0.01）. Conclusions The prevalence of decayed caries among kindergarten children in Shanghe County was high, suggesting that more emphasis should be put on improving oral health education with priority given to prevention. Further efforts should be made to increase the decayed caries filling rate.
文摘AIM: To systematically review the literature on the efficacy of noninvasive methods of arresting the progression of non-cavitated occlusal carious lesions in dentin.METHODS: The Medline/Pub Med,LILACS,Sci ELO and Scopus databases were searched to identify relevant publications through to November 2013.Only clinical trials evaluating the ability of noninvasive methods to arrest the progression of occlusal non-cavitated carious lesions in dentin were included.Screening,data extraction and quality assessment were conducted independently and in duplicate.RESULTS: Of 167 citations identified,nine full text articles were screened and five were included in the analysis.All papers reported on occlusal fissure sealing using a self-curing glass ionomer(n = 1) or resin-based(n = 4) sealant.Only the use of resin-based sealant to obliterate occlusal fissures arrested the progression of non-cavitated occlusal carious lesions in dentin.CONCLUSION: Occlusal fissure sealing with a resin-based sealant may arrest the progression of non-cavitated occlusal dentinal caries.Further clinical trials with longer follow-up times should be performed to increase scientific evidence.
