Objective: To study on Fuzheng Baozhen Decoction (FZBZD) enhancing effect of radio-and chemotherapy for malignant tumors. Methods: One hundred and Seventeen cases of malignant tumors treated with chemotherapy or/and r...Objective: To study on Fuzheng Baozhen Decoction (FZBZD) enhancing effect of radio-and chemotherapy for malignant tumors. Methods: One hundred and Seventeen cases of malignant tumors treated with chemotherapy or/and radiotherapy. Among them 55 cases were treated together with FZBZD (group A),30 cases together with Zhenqi Fuzheng Granules (group B), and the other 32 cases treated with radio-and chemotherapy alone (group C). Mechanism of FZBZD enhancing effect of chemotherapy in treating transplanted human lung adenocarcinoma (SPC-A-1) and sarcoma (S180) bearing mice was conducted experimentally. Results: Effective rates (CR + PR) of group A, B and C were 63. 6%, 43. 3 % and 37. 5% respectively, that of group A being the best (P < 0. 05). The survival quality of life was improved the most in group A (P < 0. 05).The picture of peripheral blood (WBC, Hb, PLT count) of group A after treatment was better than that of the other two groups (P < 0. 05 ). And CD3, CD4, NK activity, interleukin-2 levels were also improved more significantly in group A (P < 0. 01 ) than those in the other two. Animal experiment showed that FZBZD could improve the effect of chemotherapy in inhibiting tumor growth (P < 0. 01 ), raising cAMP/cGMP ratio (P < 0.01 ) by increasing the cAMP level in cancer tissue, and enhancing cells of G0/G1 phase and reducing cells of S phase. Conclusion: FZBZD inhibited tumor growth and enhanced the effect of radio- and chemotherapy by improving immune and hematopoietic function, cAMP/cGMP ratio and halting tumor cells in G0/G1 phase.展开更多
Condemned by Mencius （ca.372-289 BCE） as selfishness （weiwo, 为我）, Yang Zhu＇s yangsheng philosophy in China is traditionally depicted as a philosophy of egoism and hedonism. In contrast, Yang Zhu （fl.ca.370-350...Condemned by Mencius （ca.372-289 BCE） as selfishness （weiwo, 为我）, Yang Zhu＇s yangsheng philosophy in China is traditionally depicted as a philosophy of egoism and hedonism. In contrast, Yang Zhu （fl.ca.370-350 BCE） is described as an ＂early liberal or individualist＂ hero in the Western Discussion of Chinese Philosophy. Yang Zhu may not be a liberal or individualist hero as portrayed by the West, but surely he should not be depicted as a promoter of egoism as Mencius did. Both John Emerson and A.C. Graham are probably right when they claimed that Yang Zhu was a revolutionary thinker of his own time; and ＂Yang Zhu＇s intervention for the Chinese thinking world had provoked a metaphysical crisis which had threatened the basic assumptions of Confucianism and Mohism and set them into a new course＂ （A.C. Graham 1978）. From my reading, Yang Zhu＇s influence on Chinese philosophy had been and will be even greater, although his philosophy as a whole was not practiced by Chinese society in the past due to the dominance of Confucianism. Yet as the first person who clearly emphasized nourishing of life for individuals and the first theory that rooted morality into xing （性, human nature）, Yang Zhu＇s yangsheng philosophy had indeed through history made a huge contribution to Chinese nurturing life tradition, and had great potential in providing inspiration to modern moral thinking. Many discussions initiated or developed by Yang Zhu and his followers have influenced both Confucianism and Daoism profoundly. His idea of nourishing life was not only inherited and developed by Zhuangzi and later Daoist religion from life preservation perspective, but also by Mencius and Xunzi from moral cultivation perspective. As a doctrine that has shown more and more relevance to modern society, people can find many inspirations from Yang Zhu＇s answer to the following questions： What is the aim of human life？ What is the right attitude toward life and death？ What is human nature？ What is the rel展开更多
文摘Objective: To study on Fuzheng Baozhen Decoction (FZBZD) enhancing effect of radio-and chemotherapy for malignant tumors. Methods: One hundred and Seventeen cases of malignant tumors treated with chemotherapy or/and radiotherapy. Among them 55 cases were treated together with FZBZD (group A),30 cases together with Zhenqi Fuzheng Granules (group B), and the other 32 cases treated with radio-and chemotherapy alone (group C). Mechanism of FZBZD enhancing effect of chemotherapy in treating transplanted human lung adenocarcinoma (SPC-A-1) and sarcoma (S180) bearing mice was conducted experimentally. Results: Effective rates (CR + PR) of group A, B and C were 63. 6%, 43. 3 % and 37. 5% respectively, that of group A being the best (P < 0. 05). The survival quality of life was improved the most in group A (P < 0. 05).The picture of peripheral blood (WBC, Hb, PLT count) of group A after treatment was better than that of the other two groups (P < 0. 05 ). And CD3, CD4, NK activity, interleukin-2 levels were also improved more significantly in group A (P < 0. 01 ) than those in the other two. Animal experiment showed that FZBZD could improve the effect of chemotherapy in inhibiting tumor growth (P < 0. 01 ), raising cAMP/cGMP ratio (P < 0.01 ) by increasing the cAMP level in cancer tissue, and enhancing cells of G0/G1 phase and reducing cells of S phase. Conclusion: FZBZD inhibited tumor growth and enhanced the effect of radio- and chemotherapy by improving immune and hematopoietic function, cAMP/cGMP ratio and halting tumor cells in G0/G1 phase.
文摘Condemned by Mencius （ca.372-289 BCE） as selfishness （weiwo, 为我）, Yang Zhu＇s yangsheng philosophy in China is traditionally depicted as a philosophy of egoism and hedonism. In contrast, Yang Zhu （fl.ca.370-350 BCE） is described as an ＂early liberal or individualist＂ hero in the Western Discussion of Chinese Philosophy. Yang Zhu may not be a liberal or individualist hero as portrayed by the West, but surely he should not be depicted as a promoter of egoism as Mencius did. Both John Emerson and A.C. Graham are probably right when they claimed that Yang Zhu was a revolutionary thinker of his own time; and ＂Yang Zhu＇s intervention for the Chinese thinking world had provoked a metaphysical crisis which had threatened the basic assumptions of Confucianism and Mohism and set them into a new course＂ （A.C. Graham 1978）. From my reading, Yang Zhu＇s influence on Chinese philosophy had been and will be even greater, although his philosophy as a whole was not practiced by Chinese society in the past due to the dominance of Confucianism. Yet as the first person who clearly emphasized nourishing of life for individuals and the first theory that rooted morality into xing （性, human nature）, Yang Zhu＇s yangsheng philosophy had indeed through history made a huge contribution to Chinese nurturing life tradition, and had great potential in providing inspiration to modern moral thinking. Many discussions initiated or developed by Yang Zhu and his followers have influenced both Confucianism and Daoism profoundly. His idea of nourishing life was not only inherited and developed by Zhuangzi and later Daoist religion from life preservation perspective, but also by Mencius and Xunzi from moral cultivation perspective. As a doctrine that has shown more and more relevance to modern society, people can find many inspirations from Yang Zhu＇s answer to the following questions： What is the aim of human life？ What is the right attitude toward life and death？ What is human nature？ What is the rel
