During mitosis, cohesins hold the sister chromatids together until anaphase when arm cohesins are removed （Peters et al., 2008; Yao and Dai, 2012）. The shugoshin （Sgo） proteins play pivotal roles during this stage...During mitosis, cohesins hold the sister chromatids together until anaphase when arm cohesins are removed （Peters et al., 2008; Yao and Dai, 2012）. The shugoshin （Sgo） proteins play pivotal roles during this stage. There is only one shu- goshin in the fly and budding yeasts, while there are two in other organisms （including fission yeasts）. The two mamma- lian shugoshins, Sgol and Sgo2, carry out distinct functions： Sgol mainly in mitosis, and Sgo2 mainly in meiosis and perturbed mitosis. Mitotic cyclin-dependent kinase 1 （CDKI） phosphorylates Sgol, and targets the Sgol-protein phospha- tase 2A （PP2A） complex to protect centromeric cohesin （Kitajima et al., 2006; Tang et al., 2006; Liu et al., 2012）,展开更多
"We performed in the Carnegie Hall in New York City. Builders of the hall could not have dreamed that this premier venue for performing arts in the world would play host to us, a group of special performing artis..."We performed in the Carnegie Hall in New York City. Builders of the hall could not have dreamed that this premier venue for performing arts in the world would play host to us, a group of special performing artists from China. The audiences were enthralled, seeing the charms of the artists from the orient for the first time," says Zhang Jigang, art director of the China Disabled Persons’ Performing Art Troupe (CDPPAT), head of the Song and Dance Ensemble of the General Political Department of the Chinese People’s Liberation Army and the only dancer in China to have won the Century Star title.展开更多
目的探讨不同压力控制性肺膨胀（SI）对急性呼吸窘迫综合征（ARDS）患者吸痰后肺复张的影响。方法选取重庆三峡医院急救ICU科2012年9月～2014年1月的ARDS患者40例,随机分为P0、P1、P2、P3、P4组,每组各8例,分别采用0、30、35、40、45 cm...目的探讨不同压力控制性肺膨胀（SI）对急性呼吸窘迫综合征（ARDS）患者吸痰后肺复张的影响。方法选取重庆三峡医院急救ICU科2012年9月～2014年1月的ARDS患者40例,随机分为P0、P1、P2、P3、P4组,每组各8例,分别采用0、30、35、40、45 cm H2O（1 cm H2O=0.098 kPa）压力进行肺复张。记录患者吸痰后SI肺复张的呼吸力学指标及血流动力学指标。结果①P1、P2、P3、P4组肺复张后肺容积、肺动态顺应性（Cd）值明显高于P0组,差异有统计学意义（P〈0.05）;P1、P2、P3、P4组肺复张后肺复张后气道峰压（PIP）、气道平均压（Pm）、气道平台压（Pplat）明显低于P0组,差异有统计学意义（P〈0.05）;P1～P4组间差异无统计学意义（P〉0.05）。②P1、P2、P3、P4组实施SI后其平均动脉血压（MAP）、平均肺动脉压（PAP）、中心静脉压（CVP）与P0比较,差异无统计学意义（P〉0.05）。P3、P4组心率（HR）分别与P1、P2、P3组比较,差异有统计学意义（P〈0.05）。结论 30、35 cm H2O为实施SI治疗ARDS患者的适合压力。展开更多
本文讨论了 Williams,M.和 R. L . Burden的具有认知主义和社会建构主义性质的学习动机理论 ,分析了学习动机的构成要素和影响学习动机的诸多因素 ;讨论了 Dornyei的外语学习动机模式——外语学习动机与目的语层面、与学习者个体层面、...本文讨论了 Williams,M.和 R. L . Burden的具有认知主义和社会建构主义性质的学习动机理论 ,分析了学习动机的构成要素和影响学习动机的诸多因素 ;讨论了 Dornyei的外语学习动机模式——外语学习动机与目的语层面、与学习者个体层面、与学习环境层面等方面的因素紧密相关。在讨论了这些理论的基础上 。展开更多
基金supported by the grants from the Scientific Research Foundation for the Returned Overseas Chinese Scholars from State Education Ministry to J.L.,the National Nature Science Foundation of China(Nos.31271446 to J.Liao,31071190 and 31130017 to X.X.)the National Program on Key Basic Research Project(No.2013CB911002to X.X.)
文摘During mitosis, cohesins hold the sister chromatids together until anaphase when arm cohesins are removed （Peters et al., 2008; Yao and Dai, 2012）. The shugoshin （Sgo） proteins play pivotal roles during this stage. There is only one shu- goshin in the fly and budding yeasts, while there are two in other organisms （including fission yeasts）. The two mamma- lian shugoshins, Sgol and Sgo2, carry out distinct functions： Sgol mainly in mitosis, and Sgo2 mainly in meiosis and perturbed mitosis. Mitotic cyclin-dependent kinase 1 （CDKI） phosphorylates Sgol, and targets the Sgol-protein phospha- tase 2A （PP2A） complex to protect centromeric cohesin （Kitajima et al., 2006; Tang et al., 2006; Liu et al., 2012）,
文摘"We performed in the Carnegie Hall in New York City. Builders of the hall could not have dreamed that this premier venue for performing arts in the world would play host to us, a group of special performing artists from China. The audiences were enthralled, seeing the charms of the artists from the orient for the first time," says Zhang Jigang, art director of the China Disabled Persons’ Performing Art Troupe (CDPPAT), head of the Song and Dance Ensemble of the General Political Department of the Chinese People’s Liberation Army and the only dancer in China to have won the Century Star title.
文摘目的探讨不同压力控制性肺膨胀（SI）对急性呼吸窘迫综合征（ARDS）患者吸痰后肺复张的影响。方法选取重庆三峡医院急救ICU科2012年9月～2014年1月的ARDS患者40例,随机分为P0、P1、P2、P3、P4组,每组各8例,分别采用0、30、35、40、45 cm H2O（1 cm H2O=0.098 kPa）压力进行肺复张。记录患者吸痰后SI肺复张的呼吸力学指标及血流动力学指标。结果①P1、P2、P3、P4组肺复张后肺容积、肺动态顺应性（Cd）值明显高于P0组,差异有统计学意义（P〈0.05）;P1、P2、P3、P4组肺复张后肺复张后气道峰压（PIP）、气道平均压（Pm）、气道平台压（Pplat）明显低于P0组,差异有统计学意义（P〈0.05）;P1～P4组间差异无统计学意义（P〉0.05）。②P1、P2、P3、P4组实施SI后其平均动脉血压（MAP）、平均肺动脉压（PAP）、中心静脉压（CVP）与P0比较,差异无统计学意义（P〉0.05）。P3、P4组心率（HR）分别与P1、P2、P3组比较,差异有统计学意义（P〈0.05）。结论 30、35 cm H2O为实施SI治疗ARDS患者的适合压力。
文摘本文讨论了 Williams,M.和 R. L . Burden的具有认知主义和社会建构主义性质的学习动机理论 ,分析了学习动机的构成要素和影响学习动机的诸多因素 ;讨论了 Dornyei的外语学习动机模式——外语学习动机与目的语层面、与学习者个体层面、与学习环境层面等方面的因素紧密相关。在讨论了这些理论的基础上 。
