目的探讨自拟二陈汤加味方对风痰袭肺型咳嗽变异性哮喘患者气道反应性的影响。方法将我院于2015年8月—2016年7月期间收治的128例风痰袭肺型咳嗽变异性哮喘患者随机分为两组,即对照组和治疗组,均64例。对照组采用复方甲氧那明胶囊治疗,...目的探讨自拟二陈汤加味方对风痰袭肺型咳嗽变异性哮喘患者气道反应性的影响。方法将我院于2015年8月—2016年7月期间收治的128例风痰袭肺型咳嗽变异性哮喘患者随机分为两组,即对照组和治疗组,均64例。对照组采用复方甲氧那明胶囊治疗,治疗组采用自拟二陈汤加味方治疗。比较治疗前后两组临床症状、肺功能指标[1 s用力呼气量与用力肺活量比值(forced expiratory volume in one second to forced vital capacity ratio,FEV1%)]、气道反应性指标[第一秒用力呼气容积降低20%所需的药物累积量(The cumulative amount of drug required to reduce the forced expiratory volume in the first second by 20%,PD20FEV1)]的变化情况及不良反应发生情况,并评价两组临床疗效。结果与治疗前比较,对照组和治疗组中医证候积分在治疗后均明显下降,而FEV1%、PD20FEV1明显上升,且治疗组上述观察指标均优于对照组,差异有统计学意义(P <0. 05);治疗组临床疗效总有效率为96. 88%(62/64),明显高于对照组79. 69%(51/64),差异有统计学意义(P <0. 05);治疗组不良反应发生率为1. 56%(1/64),明显低于对照组12. 50%(8/64),差异有统计学意义(P <0. 05)。结论采用自拟二陈汤加味方治疗风痰袭肺型咳嗽变异性哮喘,可显著提高临床疗效,缓解临床症状,降低气道反应性,改善肺功能,促进患者身体恢复,值得临床大力推广。展开更多
OBJECTIVE: To observe the effect of Modified Erchen Decoction on cervical spondylotic vertebral arteriopathy with stagnation and blockade of phlegm-dampness syndrome and effects on cerebral blood flow parameters. METH...OBJECTIVE: To observe the effect of Modified Erchen Decoction on cervical spondylotic vertebral arteriopathy with stagnation and blockade of phlegm-dampness syndrome and effects on cerebral blood flow parameters. METHODS: A total of 80 cervical spondylotic vertebral arteriopathy(CSA) patients with stagnation and blockade of phlegmdampness syndrome admitted to our hospital from October 2016 to April 2017 were selected and randomly divided into observation group and control group, with 40 cases in each group. The observation group was treated with Modified Erchen Decoction and the control group was given conventional treatment with Western medicine. After 4 weeks of treatment, the main clinical symptoms and signs(vertigo, neck and shoulder pain, headache, psychological and social adjustment, daily life and work) and cerebral blood flow parameters [the peak values of intracranial vertebral-basal artery diastolic blood flow velocity(Vd) and systolic blood flow velocity(Vp)] were compared between the 2 groups. The total clinical effective rate and adverse reactions during treatment were also compared. RESULTS: After treatment, the total effective rate of the observation group was 90.0%, which was significantly higher than that of the control group(77.5%). The difference between the two groups was statistically significant(P < 0.05). After treatment, The scores of vertigo, neck and shoulder pain, headache, psychology and society adaptation, daily life and work were significantly increased(P < 0.05), and the above scores of the observation group were increased more obviously. The difference between the groups was statistically significant(P < 0.05). After treatment, the levels of Vd and Vp were significantly increased(P < 0.05), and the increase of the above indexes was more obvious in the observation group. The difference between the 2 groups was statistically significant(P < 0.05). There were no significant abnormalities in blood routine, urine routine, liver function and renal function. There was no significant diffe展开更多
文摘目的探讨自拟二陈汤加味方对风痰袭肺型咳嗽变异性哮喘患者气道反应性的影响。方法将我院于2015年8月—2016年7月期间收治的128例风痰袭肺型咳嗽变异性哮喘患者随机分为两组,即对照组和治疗组,均64例。对照组采用复方甲氧那明胶囊治疗,治疗组采用自拟二陈汤加味方治疗。比较治疗前后两组临床症状、肺功能指标[1 s用力呼气量与用力肺活量比值(forced expiratory volume in one second to forced vital capacity ratio,FEV1%)]、气道反应性指标[第一秒用力呼气容积降低20%所需的药物累积量(The cumulative amount of drug required to reduce the forced expiratory volume in the first second by 20%,PD20FEV1)]的变化情况及不良反应发生情况,并评价两组临床疗效。结果与治疗前比较,对照组和治疗组中医证候积分在治疗后均明显下降,而FEV1%、PD20FEV1明显上升,且治疗组上述观察指标均优于对照组,差异有统计学意义(P <0. 05);治疗组临床疗效总有效率为96. 88%(62/64),明显高于对照组79. 69%(51/64),差异有统计学意义(P <0. 05);治疗组不良反应发生率为1. 56%(1/64),明显低于对照组12. 50%(8/64),差异有统计学意义(P <0. 05)。结论采用自拟二陈汤加味方治疗风痰袭肺型咳嗽变异性哮喘,可显著提高临床疗效,缓解临床症状,降低气道反应性,改善肺功能,促进患者身体恢复,值得临床大力推广。
文摘OBJECTIVE: To observe the effect of Modified Erchen Decoction on cervical spondylotic vertebral arteriopathy with stagnation and blockade of phlegm-dampness syndrome and effects on cerebral blood flow parameters. METHODS: A total of 80 cervical spondylotic vertebral arteriopathy(CSA) patients with stagnation and blockade of phlegmdampness syndrome admitted to our hospital from October 2016 to April 2017 were selected and randomly divided into observation group and control group, with 40 cases in each group. The observation group was treated with Modified Erchen Decoction and the control group was given conventional treatment with Western medicine. After 4 weeks of treatment, the main clinical symptoms and signs(vertigo, neck and shoulder pain, headache, psychological and social adjustment, daily life and work) and cerebral blood flow parameters [the peak values of intracranial vertebral-basal artery diastolic blood flow velocity(Vd) and systolic blood flow velocity(Vp)] were compared between the 2 groups. The total clinical effective rate and adverse reactions during treatment were also compared. RESULTS: After treatment, the total effective rate of the observation group was 90.0%, which was significantly higher than that of the control group(77.5%). The difference between the two groups was statistically significant(P < 0.05). After treatment, The scores of vertigo, neck and shoulder pain, headache, psychology and society adaptation, daily life and work were significantly increased(P < 0.05), and the above scores of the observation group were increased more obviously. The difference between the groups was statistically significant(P < 0.05). After treatment, the levels of Vd and Vp were significantly increased(P < 0.05), and the increase of the above indexes was more obvious in the observation group. The difference between the 2 groups was statistically significant(P < 0.05). There were no significant abnormalities in blood routine, urine routine, liver function and renal function. There was no significant diffe
