Background Primary open angle glaucoma （POAG） is a common cause of irreversible blindness. The variable etiology of POAG poses significant challenges for treatment and rehabilitation. We analyzed a large POAG patien...Background Primary open angle glaucoma （POAG） is a common cause of irreversible blindness. The variable etiology of POAG poses significant challenges for treatment and rehabilitation. We analyzed a large POAG patient cohort during treatment to reveal possible causes of vision disorder, assess vision-related quality of life （VRQL）, and to evaluate the efficacy of rehabilitative treatments. Methods We analyzed the visional disturbances in 500 POAG patients （890 eyes） by regular ophthalmic examination and visual field examination using Humphrey 30-o perimetry. Appropriate rehabilitative treatments for POAG were prescribed based on results of clinical examination and included correction of ametropia, health education, counseling, and the fitting of typoscopes. VRQL was assessed before and after treatment by a VRQL self-assessment questionnaire. Results Scores on the VRQL self-assessment were significantly lower compared to healthy controls. The primary cause of the vision disturbances was ametropia （97.99%）, and 51.61% of the ametropia eyes had not received appropriate correction. The secondary causes of visual impairment were glaucomatous neurodegeneration （26.29%）, complicated cataract, or other accompanying eye diseases. The causes of the clinical low vision （44 patients） were glaucomatous neurodegeneration （32 eyes）, fundus diseases （23 eyes）, keratopathy （11 eyes）, and other eye diseases （10 eyes）. The VRQL scores of patients improved significantly after rehabilitation and the correction of ametropia （P 〈0.01）. Twenty-five patients with low vision were provided with typoscopes, and 21 （84%） experienced significant functional recovery, while the remaining low vision patients could see letter lines two or more levels lower （smaller） on visual charts in a near vision test. Conclusions Vision disorders in POAG patients are common and severe. Appropriate rehabilitation, especially the correction of ametropia, can significantly improve VRQL as revealed by the self-展开更多
目的探讨非斜视性双眼视异常学龄儿童生活质量量表(Quality-of-Life Scale for School-Age Children With Functional Abnormalities in Binocular Vision,QOL-CFA20)在非斜视性双眼视异常学龄儿童生活质量状况评估及早期诊断中的应用...目的探讨非斜视性双眼视异常学龄儿童生活质量量表(Quality-of-Life Scale for School-Age Children With Functional Abnormalities in Binocular Vision,QOL-CFA20)在非斜视性双眼视异常学龄儿童生活质量状况评估及早期诊断中的应用价值。方法选取非斜视性双眼视异常学龄儿童134例和正常儿童120例,分别行QOL-CFA20量表及视功能指数量表(Vison Function-14,VF-14)调查。结果QOL-CFA20量表与VF-14量表得分呈负相关(P<0.01),VF-14=5.149~0.299(QOL-CFA20量表得分)。QOL-CFA20量表最佳临界值为56分,灵敏度、特异度分别为0.948、0.918,曲线下面积为0.959,预测效度优于VF-14。结论 QOL-CFA20量表在非斜视性双眼视异常学龄儿童生活质量状况评估中的最佳临界值为56分,是非斜视性双眼视异常学龄儿童生活质量状况评测的有效工具。展开更多
文摘Background Primary open angle glaucoma （POAG） is a common cause of irreversible blindness. The variable etiology of POAG poses significant challenges for treatment and rehabilitation. We analyzed a large POAG patient cohort during treatment to reveal possible causes of vision disorder, assess vision-related quality of life （VRQL）, and to evaluate the efficacy of rehabilitative treatments. Methods We analyzed the visional disturbances in 500 POAG patients （890 eyes） by regular ophthalmic examination and visual field examination using Humphrey 30-o perimetry. Appropriate rehabilitative treatments for POAG were prescribed based on results of clinical examination and included correction of ametropia, health education, counseling, and the fitting of typoscopes. VRQL was assessed before and after treatment by a VRQL self-assessment questionnaire. Results Scores on the VRQL self-assessment were significantly lower compared to healthy controls. The primary cause of the vision disturbances was ametropia （97.99%）, and 51.61% of the ametropia eyes had not received appropriate correction. The secondary causes of visual impairment were glaucomatous neurodegeneration （26.29%）, complicated cataract, or other accompanying eye diseases. The causes of the clinical low vision （44 patients） were glaucomatous neurodegeneration （32 eyes）, fundus diseases （23 eyes）, keratopathy （11 eyes）, and other eye diseases （10 eyes）. The VRQL scores of patients improved significantly after rehabilitation and the correction of ametropia （P 〈0.01）. Twenty-five patients with low vision were provided with typoscopes, and 21 （84%） experienced significant functional recovery, while the remaining low vision patients could see letter lines two or more levels lower （smaller） on visual charts in a near vision test. Conclusions Vision disorders in POAG patients are common and severe. Appropriate rehabilitation, especially the correction of ametropia, can significantly improve VRQL as revealed by the self-
文摘目的探讨非斜视性双眼视异常学龄儿童生活质量量表(Quality-of-Life Scale for School-Age Children With Functional Abnormalities in Binocular Vision,QOL-CFA20)在非斜视性双眼视异常学龄儿童生活质量状况评估及早期诊断中的应用价值。方法选取非斜视性双眼视异常学龄儿童134例和正常儿童120例,分别行QOL-CFA20量表及视功能指数量表(Vison Function-14,VF-14)调查。结果QOL-CFA20量表与VF-14量表得分呈负相关(P<0.01),VF-14=5.149~0.299(QOL-CFA20量表得分)。QOL-CFA20量表最佳临界值为56分,灵敏度、特异度分别为0.948、0.918,曲线下面积为0.959,预测效度优于VF-14。结论 QOL-CFA20量表在非斜视性双眼视异常学龄儿童生活质量状况评估中的最佳临界值为56分,是非斜视性双眼视异常学龄儿童生活质量状况评测的有效工具。
