<strong>Objective</strong><span style="font-family:Verdana;"><strong>:</strong></span><span style="font-family:Verdana;"> To investigate the correlation be...<strong>Objective</strong><span style="font-family:Verdana;"><strong>:</strong></span><span style="font-family:Verdana;"> To investigate the correlation between deep static color Doppler ultrasound of both lower extremities combined with fibrinolytic system detection in pregnancy-induced hypertension.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Methods</span></b><b><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> A total of 70 normal pregnant women, 70 pregnant women with hypertension during pregnancy, and 50 healthy non-pregnant women in the same period were selected as the research objects. The deep veins of both lower limbs were examined by Rili Erlangshen’s color Doppler ultrasound diagnostic instrument (CDU),</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">and the </span><span style="font-family:Verdana;">fibrinolysis system was tested by enzyme-linked immunosorbent assay (ELISA) </span><span style="font-family:Verdana;">method and </span><a name="OLE_LINK12"></a><span style="font-family:Verdana;">automatic hemagglutination analyzer.</span><b><span style="font-family:Verdana;"> Results</span></b></span><b><span style="font-family:Verdana;">:</span></b><b><span style="font-family:""> </span></b><span style="font-family:Verdana;">Compared with the non-pregnant group, the inner diameters of the left/right femoral vein (CFV) and popliteal vein (POV) in the normal pregnancy group and the pregnancy-induced hypertension group were significantly widened, and the peak blood flow spectrum was significantly reduced. The difference was statistically significant (P < 0.01);FIB, PLG, t-PA, PAI, D-Dimer were significantly increased, the difference was statistically significant (P < 0.01);Compared with the normal pregnancy group, the inner diameter of the left/right femoral vein (CFV) in the hypertensive pregnancy group was significantly wider than that in the normal pregnancy group, and the peak 展开更多
目的:分析凝血功能、纤溶指标在妊娠高血压中的表达及给予联合用药后的变化。方法:选择本院2021年8月至2022年8月收治的妊娠期高血压患者84例为观察组,在同一时期选择于本院就诊的健康孕妇84例为对照组,检测并对比观察组及对照组的凝血...目的:分析凝血功能、纤溶指标在妊娠高血压中的表达及给予联合用药后的变化。方法:选择本院2021年8月至2022年8月收治的妊娠期高血压患者84例为观察组,在同一时期选择于本院就诊的健康孕妇84例为对照组,检测并对比观察组及对照组的凝血功能、纤溶指标,之后根据患者高血压严重程度将观察组划分为轻度高血压(n=28)、中度高血压(n=28)以及子痫前期(n=28),对比不同高血压严重程度患者的凝血功能以及纤溶指标,最后给予观察组药物治疗,对比联合用药前、后观察组患者凝血功能、纤溶指标变化情况,借助受试者工作(receiver operating characteristic,ROC)曲线评估诊断效能。结果:两组受试者凝血功能、纤溶指标对比差异有统计学意义(P<0.05)。与治疗前相比,治疗后三组高血压患者的凝血功能、纤溶指标均有所下降,三组高血压患者凝血功能以及纤溶指标对比差异有统计学意义(P<0.05)。ROC曲线分析结果显示,PT的曲线下面积(area under curve,AUC)为1.000,其灵敏度以及特异度分别为100.00%、100.00%,高于其他指标检测的水平。结论:凝血、纤溶指标与妊娠期高血压发病之间存在密切关系,能够为早期妊娠期高血压患者的诊断、治疗提供数据参考,并在治疗后期起到评估预后的作用。展开更多
文摘<strong>Objective</strong><span style="font-family:Verdana;"><strong>:</strong></span><span style="font-family:Verdana;"> To investigate the correlation between deep static color Doppler ultrasound of both lower extremities combined with fibrinolytic system detection in pregnancy-induced hypertension.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Methods</span></b><b><span style="font-family:Verdana;">:</span></b><span style="font-family:Verdana;"> A total of 70 normal pregnant women, 70 pregnant women with hypertension during pregnancy, and 50 healthy non-pregnant women in the same period were selected as the research objects. The deep veins of both lower limbs were examined by Rili Erlangshen’s color Doppler ultrasound diagnostic instrument (CDU),</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">and the </span><span style="font-family:Verdana;">fibrinolysis system was tested by enzyme-linked immunosorbent assay (ELISA) </span><span style="font-family:Verdana;">method and </span><a name="OLE_LINK12"></a><span style="font-family:Verdana;">automatic hemagglutination analyzer.</span><b><span style="font-family:Verdana;"> Results</span></b></span><b><span style="font-family:Verdana;">:</span></b><b><span style="font-family:""> </span></b><span style="font-family:Verdana;">Compared with the non-pregnant group, the inner diameters of the left/right femoral vein (CFV) and popliteal vein (POV) in the normal pregnancy group and the pregnancy-induced hypertension group were significantly widened, and the peak blood flow spectrum was significantly reduced. The difference was statistically significant (P < 0.01);FIB, PLG, t-PA, PAI, D-Dimer were significantly increased, the difference was statistically significant (P < 0.01);Compared with the normal pregnancy group, the inner diameter of the left/right femoral vein (CFV) in the hypertensive pregnancy group was significantly wider than that in the normal pregnancy group, and the peak
文摘目的:分析凝血功能、纤溶指标在妊娠高血压中的表达及给予联合用药后的变化。方法:选择本院2021年8月至2022年8月收治的妊娠期高血压患者84例为观察组,在同一时期选择于本院就诊的健康孕妇84例为对照组,检测并对比观察组及对照组的凝血功能、纤溶指标,之后根据患者高血压严重程度将观察组划分为轻度高血压(n=28)、中度高血压(n=28)以及子痫前期(n=28),对比不同高血压严重程度患者的凝血功能以及纤溶指标,最后给予观察组药物治疗,对比联合用药前、后观察组患者凝血功能、纤溶指标变化情况,借助受试者工作(receiver operating characteristic,ROC)曲线评估诊断效能。结果:两组受试者凝血功能、纤溶指标对比差异有统计学意义(P<0.05)。与治疗前相比,治疗后三组高血压患者的凝血功能、纤溶指标均有所下降,三组高血压患者凝血功能以及纤溶指标对比差异有统计学意义(P<0.05)。ROC曲线分析结果显示,PT的曲线下面积(area under curve,AUC)为1.000,其灵敏度以及特异度分别为100.00%、100.00%,高于其他指标检测的水平。结论:凝血、纤溶指标与妊娠期高血压发病之间存在密切关系,能够为早期妊娠期高血压患者的诊断、治疗提供数据参考,并在治疗后期起到评估预后的作用。
