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Traditional Chinese Medicine syndrome-related herbal prescriptions in treatment of malignant tumors 被引量:8
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作者 Zhizhen Liu Songyi Chen +7 位作者 Jing Cai Enda Zhang Lan Lan Junting Zheng Lianming Liao Xuemei Yang Changen Zhou Jian Du 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2013年第1期19-26,共8页
OBJECTIVE: To investigate the distribution characteristics of TCM syndromes and the related herbal prescriptions for malignant tumors (MT). METHODS: A clinical database of the TCM syndromes and the herbal prescrip... OBJECTIVE: To investigate the distribution characteristics of TCM syndromes and the related herbal prescriptions for malignant tumors (MT). METHODS: A clinical database of the TCM syndromes and the herbal prescriptions in treatment of 136 MT patients were established. The data were then analyzed using cluster and frequency analysis. RESULTS: According to the cluster analysis, the TCM syndromes in MT patients mainly included two patterns: deficiency of both Qi and Yin and internal accumulation of toxic heat. The commonlyprescribed herbs were Huangqi (Astraglus), Nuizhenzi (Fructus Ligustri Lucidi), Lingzhi (Ganoderma Lucidum), Huaishan (Dioscorea Opposita), Xiakucao (Prunella Vulgaris), and Baihuasheshecao (Herba Hedyotidis). CONCLUSION: Deficiency of Qi and Yin is the pri- mary syndrome of MT, and internal accumulation of toxic heat is the secondary syndrome. The herbs for Qi mainly heat-cl supplementation and Yin houris used, with earance and the assistance of detoxification. hment are herbs for 展开更多
关键词 CARCINOMA SYNDROMES benefiting QiOr nourishing Yin Complementary therapies Clus-er analysis Data mining
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活血化瘀法和补益法协同在肿瘤化疗后骨髓抑制中的运用 被引量:8
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作者 谭彩 王理槐 +2 位作者 冯君 王伟松 刘建和 《湖南中医药大学学报》 CAS 2022年第1期82-85,共4页
骨髓抑制是恶性肿瘤化疗后的常见不良反应。化疗药物入血,损伤血络,致血脉空虚、气血瘀滞,加上化疗后元气虚衰,无力推动血液运行,致使血停而为瘀,影响新血生成,"瘀血不去,新血不生"。因此,临证中在补益正气的前提下,同时因人... 骨髓抑制是恶性肿瘤化疗后的常见不良反应。化疗药物入血,损伤血络,致血脉空虚、气血瘀滞,加上化疗后元气虚衰,无力推动血液运行,致使血停而为瘀,影响新血生成,"瘀血不去,新血不生"。因此,临证中在补益正气的前提下,同时因人制宜、辨证活血化瘀,使益气与行血并行,可祛瘀生新、推陈出新,促进骨髓造血,从而可有效改善骨髓抑制。 展开更多
关键词 肿瘤 化疗 骨髓抑制 活血化瘀 补益 祛瘀生新
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BENEFITING FROM BOTH THE COMMUNICATIVE APPROACHES AND THE TRADITIONAL CHINESE METHODS IN ELT 被引量:5
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作者 Xu Ping Suzhou University,Jiangsu 《Chinese Journal of Applied Linguistics》 1999年第2期4-9,共6页
For some time,ELT in China has been undergoing a heated discussion as to the best way ofteaching.Some think that the communicative approaches is inappropriate while others think that the tra-ditional Chinese methods a... For some time,ELT in China has been undergoing a heated discussion as to the best way ofteaching.Some think that the communicative approaches is inappropriate while others think that the tra-ditional Chinese methods are too old-fashioned.From various points of view,this paper argues that boththe communicative approach and the traditional Chinese methods can co-exist and influence each other inthe present Chinese teaching context. 展开更多
关键词 benefiting FROM BOTH THE COMMUNICATIVE APPROACHES AND THE TRADITIONAL CHINESE METHODS IN ELT
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Effect of Yiqiyangyin recipe on heparanase and nephrin in rats with adriamycin-induced nephropathy 被引量:4
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作者 Wen Sun Yongrui He +6 位作者 Jian Yu Yanyan Lin Yonghong Wang Xia Gao Ying Wang Zhonghua Zhao Xueguang Liu 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2013年第3期334-342,共9页
OBJECTIVE: To discuss the mechanism of Yiqiyang- yin recipe in rats with adriamycin (ADR)-induced ne- phropathyo METHODS: We randomly divided 30 Sprague-Daw- ley rats into 5 groups: control, model, glucocorti- co... OBJECTIVE: To discuss the mechanism of Yiqiyang- yin recipe in rats with adriamycin (ADR)-induced ne- phropathyo METHODS: We randomly divided 30 Sprague-Daw- ley rats into 5 groups: control, model, glucocorti- coid, Chinese herb, and Chinese herb plus glucocor- ticoid groups. The 24-h urine volume was collected on days 7, 14, 21, and 28 after ADR injection, and all rats were killed on day 28. We measured the 24-h levels of urinary protein, serum cholesterol, and se- rum triglycerides, and renal function of all rats by using routine biochemical methods. Pathological changes in the rat kidneys were observed under light and electron microscopes. Heparanase (HPA) mRNA expression levels were measured using re-al-time fluorescence-quantitative polymerase chain reaction. Urine levels of HPA in all groups were measured using enzyme-linked immunosor- bent assay. The expression of nephrin was detected by immunohistochemical staining and quantitative- ly analyzed using Motic image analysis 3.2 software. RESULTS: The levels of urinary protein and serum triglycerides and cholesterol in rats with ADR-in- duced nephropathy increased on day 14. The se- rum albumin levels simultaneously decreased. All the changes reached the peak on day 28. Examina- tion under the light microscope showed inflamma- tory cells and slight fibroplasia in the renal intersti- tium in the model group, but fewer inflammatory cells were observed in the intervention groups than those in the model group. Examination under the electron microscope showed extensive fusion of foot processes in ADR rats. HPA mRNA expres- sion was higher in the model group than that in the control group. The HPA mRNA levels in the in- tervention groups, especially in the Chinese herb group, and Chinese herb plus glucocorticoid group were significantly lower than the level in the model group. The HPA expression levels correlated signifi- cantly with the proteinuria level. No significant dif- ference was found in the HPA level in urine be- tween the intervention gro 展开更多
关键词 benefiting Qi for nourishing Yin Chi-nese medical formula DOXORUBICIN PROTEINURIA HEPARANASE NEPHRIN
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Clinical observation of cerebral palsy treated with Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy 被引量:4
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作者 刘振寰 赵勇 +2 位作者 罗冠君 李诺 招文健 《World Journal of Acupuncture-Moxibustion》 2009年第2期22-29,共8页
Objective To observe the effects on the range of motion (ROM) of ankle joint and muscular spasm of the lower limbs treated with Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthen... Objective To observe the effects on the range of motion (ROM) of ankle joint and muscular spasm of the lower limbs treated with Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy in infantile cerebral palsy (CP). Methods In 286 cases of spasmodic CP, 7 kinds of Chinese massage were adopted, named massage on acupoints to promote circulation of the Governor Vessel, massage for strengthening the spleen and benefiting qi, spine-pinching therapy, segmental massage, foot massage, massage for promoting the recovery of muscle strength and massage for promoting ROM of joints. Chinese massage was applied in musical background. Buddha music and five-element music of Chinese medicine (music of the Heart, Liver and Kidney Meridians) were optioned. The treatment was given once or twice a day and 30 days made one course. The angles of femoral adductor and dorsal flexion of foot as well as the score of composite spasticity scale (CSS) were observed before and after treatment so that the therapeutic effect was assessed. Results In 30 days of treatment, 106 cases (37. 1%) were effective markedly, 172 cases (60. 1%) effective and 8 cases (2.8%) failed. The angle of dorsal flexion of foot was (105.64± 12.66)° and (76.58± 9.89)° before and after treatment respectively; the angle of femoral adductor was (119.89±25.47)° and (158.99± 18.66)° before and after treatment respectively; the score of CSS was (12.39±2.56) and (7. 069 ± 2.97) before and after treatment respectivel, there was significant difference before and after treatment (all P〈0.01). Conclusion Chinese massage for promoting the Governor Vessel, benefiting the kidney and strengthening the spleen combined with music therapy brings the extremely active effect into play on the recovery of sitting, kneeling, standing and walking for children with CP. 展开更多
关键词 Cerebral Palsy (CP) Promoting the Governor Vessel and benefiting the Kidney Range of Motion (ROM) Music Therapy Composite Spasticity Scale (CSS)
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不同时间窗中药对血管性痴呆小鼠脑神经递质的影响 被引量:3
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作者 孙丽芳 张丽欣 高红 《河北中医药学报》 2014年第1期4-5,50,共3页
目的:探讨中药益气活血方治疗脑缺血再灌注损伤致血管性痴呆小鼠的最佳时间。方法:利用反复结扎双侧颈总动脉方式建立缺血再灌注血管性痴呆小鼠模型,经不同时间窗的益气活血方治疗后,观察模型小鼠脑神经递质去甲肾上腺素(NE)、多巴胺(DA... 目的:探讨中药益气活血方治疗脑缺血再灌注损伤致血管性痴呆小鼠的最佳时间。方法:利用反复结扎双侧颈总动脉方式建立缺血再灌注血管性痴呆小鼠模型,经不同时间窗的益气活血方治疗后,观察模型小鼠脑神经递质去甲肾上腺素(NE)、多巴胺(DA)、5-羟色胺(5-TH)的含量。结果:益气活血方即刻治疗组、3天后治疗组均可增加脑组织中去甲肾上腺素(NE)、多巴胺(DA)、5-羟色胺(5-TH)的含量,对缺血再灌注血管性痴呆小鼠有一定的保护作用,其中即刻治疗组疗效最佳。结论:中药益气活血方治疗血管性痴呆的最佳时间以即刻为最好,3天以内均可有一定的效果,在条件许可的情况下,应采取尽早治疗的原则。 展开更多
关键词 益气活血方 补阳还五汤 中药 血管性痴呆 时间窗 脑神经递质 缺血再灌注 Yiqi Huoxue formula ( benefiting qi for ACTIVATING blood circulation )
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Top-Level Design of Smart City Based on“Integration of Four Plans”
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作者 Jianbo Cheng Peng Sun 《ZTE Communications》 2015年第4期34-39,共6页
A smart city provides a new idea and model for urban construction, management, and development. This article proposes the concepts and methodology for top-level design of smart cities based on the " Integration of Fo... A smart city provides a new idea and model for urban construction, management, and development. This article proposes the concepts and methodology for top-level design of smart cities based on the " Integration of Four Plans ", and the planning process and systems for implementing the top-level design of smart cities. This article discusses, from the perspective of a city, how to optimize resource allocation, coordinate the development of urban economy, society, resources, environment, and people's livelihood, and map out the blueprints for healthy and sustainable development of a smart city. 展开更多
关键词 smart city top-level design integration of Four Plans ICT benefiting People
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Case of professor Xu ZOU’s acupuncture technique for“benefiting kidney and strengthening anti-pathogenic qi”in promoting the absorption of COVID-19 被引量:2
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作者 Lan-ting TAO Tao-liang HUANG +1 位作者 Dan-wen ZHENG Xu ZOU 《World Journal of Acupuncture-Moxibustion》 CSCD 2020年第3期167-170,共4页
A case of the absorption of corona virus disease 2019(COVID-19)promoted by professor Xu ZOU’s acupuncture technique for"benefiting kidney and strengthening anti-pathogenic qi"is introduced.A female patient ... A case of the absorption of corona virus disease 2019(COVID-19)promoted by professor Xu ZOU’s acupuncture technique for"benefiting kidney and strengthening anti-pathogenic qi"is introduced.A female patient suffered from COVID-19,64 years old,had been treated with acupuncture and Chinese herb granules for 10 days on the base of the oral administration of moxifloxacin.In the re-examination,the chest CT image indicated that the absorption of COVID-19 was obvious as compared with before,the nucleic acid test of novel corona virus was negative and the patient narrated no obvious discomfort.Acupuncture therapy plays its active adjuvant effect in the whole process of the treatment of COVID-19. 展开更多
关键词 benefiting kidney and strengthening anti-pathogenic qi ACUPUNCTURE Chinese herbal granules Corona virus disease 2019(COVID-19)
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Deepening China-Africa Cooperation, Benefiting People’s Health 被引量:1
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作者 Li Bin 《ChinAfrica》 2015年第12期14-15,共2页
CHINA and Africa have been a commu- nity of shared interests and shared destiny Their collaboration benefits not only the development of China and Africa but also promotes the unity and cooperation of developing count... CHINA and Africa have been a commu- nity of shared interests and shared destiny Their collaboration benefits not only the development of China and Africa but also promotes the unity and cooperation of developing countries. Health cooperation is a powerful testimony to the friendship between Chinese and African people. Based on win-win cooperation and aiming at the well-being of the people, China and Africa have attained fruitful results through health cooperation over the last five decades. 展开更多
关键词 Deepening China-Africa Cooperation benefiting People’s Health
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马克思主义金融理论及其当代启示——共生与分利的视角 被引量:1
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作者 张敏 《改革与战略》 北大核心 2016年第6期25-28,共4页
马克思《资本论》中对金融本质问题的研究发人深省,近年来西方左翼学者关于"金融化"的研究一定程度上继承了马克思的衣钵。与传统金融发展理论相比,马克思主义金融理论更注重从金融的本质出发研究金融现象。沿着马克思主义的... 马克思《资本论》中对金融本质问题的研究发人深省,近年来西方左翼学者关于"金融化"的研究一定程度上继承了马克思的衣钵。与传统金融发展理论相比,马克思主义金融理论更注重从金融的本质出发研究金融现象。沿着马克思主义的分析思路,文章从共生与分利的视角研究金融与实体经济的关系,试图把握金融的本质、研判金融发展趋势。 展开更多
关键词 金融资本 金融化 共生 分利
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百色水利枢纽工程任务和目标的调整 被引量:1
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作者 何素明 《广西水利水电》 2014年第5期30-33,45,共5页
已建的广西百色水利枢纽是治理和开发郁江的关键性水利工程,原设计工程任务是以防洪为主,兼顾发电、灌溉、航运、供水等综合利用。随着西部大开发深入,广西经济社会的发展对百色水利枢纽提出了更高要求。分析了区域经济社会发展对百色... 已建的广西百色水利枢纽是治理和开发郁江的关键性水利工程,原设计工程任务是以防洪为主,兼顾发电、灌溉、航运、供水等综合利用。随着西部大开发深入,广西经济社会的发展对百色水利枢纽提出了更高要求。分析了区域经济社会发展对百色水利枢纽工程防洪、水资源配置任务和目标调整的要求,并提出开展满足调整后工程任务、目标要求的防洪、兴利调度方式研究的建议。 展开更多
关键词 任务 目标 防洪 兴利 调度 方式 百色水利枢纽
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Protecting and Benefiting
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作者 LI LI 《Beijing Review》 2010年第16期22-24,共3页
Huangshan City endeavors to protect its natural views and ancient culture while tapping its tourism
关键词 Protecting and benefiting
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A summary of research on benefiting Qi and activating blood to regulate mitophagy to prevent and treat ischemic heart disease
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作者 Ye-Hui He Jian-Qi Lu 《Journal of Hainan Medical University》 2020年第10期65-68,共4页
Ischemic heart disease has the characteristics of high morbidity and high mortality, which seriously endangers people's health. Mitophagy can selectively remove damaged organelles, and has a role in maintaining th... Ischemic heart disease has the characteristics of high morbidity and high mortality, which seriously endangers people's health. Mitophagy can selectively remove damaged organelles, and has a role in maintaining the homeostasis of myocardial cells and protecting ischemic myocardium. Significance. More and more studies have found that traditional Chinese medicine can improve ischemic damage of cardiomyocytes by regulating mitochondrial function and autophagy. Using mitochondria as the target of traditional Chinese medicine in cardiomyocytes to explore the treatment of ischemic Effective measures for heart disease have become a hotspot for related Chinese medicine workers. Based on the above background, this article outlines the main regulatory pathways of mitochondrial autophagy, and reviews related researches on traditional Chinese medicine of benefiting qi and activating blood and mitophagy in this field. 展开更多
关键词 TRADITIONAL Chinese medicine benefiting qi and activating blood MITOPHAGY Ischemic heart disease
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Benefiting All
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作者 LI LI 《Beijing Review》 2010年第45期26-27,共2页
A new law promotes individual equality in social security benefits and forbids the misuse of funds The Standing Committee of the National People’s Congress (NPC),China’s top legislature, voted to adopt a social insu... A new law promotes individual equality in social security benefits and forbids the misuse of funds The Standing Committee of the National People’s Congress (NPC),China’s top legislature, voted to adopt a social insurance law on October 28 that prevents 展开更多
关键词 benefiting All
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Benefiting From Culture
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作者 Li Jing 《ChinAfrica》 2019年第8期30-31,共2页
Driving from the urban area of Liping County in southwest China's Guizhou Province along the rugged mountainous road for four hours, which is actually only 100 km, one can see the small, primitive Gaibao Village, ... Driving from the urban area of Liping County in southwest China's Guizhou Province along the rugged mountainous road for four hours, which is actually only 100 km, one can see the small, primitive Gaibao Village, mainly inhabited by the Dong ethnic minority. 展开更多
关键词 benefiting CULTURE ETHNIC MINORITY
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从休谟法则到企业的二重维度
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作者 杨豹 《石家庄经济学院学报》 2007年第2期117-120,共4页
18世纪30年代,休谟在他的代表作《人性论》中指出:从“是”与“不是”的关系推不出“应该”、“不应该”的关系,从事实的真假推不出道德价值。它揭示出市场竞争中企业经济行为的二重维度,即求德与求利的二律背反。笔者将从自然主义、直... 18世纪30年代,休谟在他的代表作《人性论》中指出:从“是”与“不是”的关系推不出“应该”、“不应该”的关系,从事实的真假推不出道德价值。它揭示出市场竞争中企业经济行为的二重维度,即求德与求利的二律背反。笔者将从自然主义、直觉主义、情感主义、规定主义对休谟法则的探索,提出解决求德与求利一致性的理论根据和实践根据,并从现行企业的缺陷及其发展现状来构建企业二重维度的模式设计。 展开更多
关键词 休谟法则 企业伦理 应该 求德 求利
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AGEs-RAGE信号通路在糖尿病肾病中的作用机制及中医药研究进展 被引量:155
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作者 杨超茅 杨志新 马晓玲 《中医学报》 CAS 2019年第9期1864-1868,共5页
糖尿病肾病是临床常见的糖尿病并发症,是导致终末期肾脏病的主要原因之一,也是糖尿病患者致死的重要因素之一。晚期糖基化终末产物(advanced glycosylation end products,AGEs)-糖基化终末产物受体(receptor of AGEs,RAGE)信号通路是糖... 糖尿病肾病是临床常见的糖尿病并发症,是导致终末期肾脏病的主要原因之一,也是糖尿病患者致死的重要因素之一。晚期糖基化终末产物(advanced glycosylation end products,AGEs)-糖基化终末产物受体(receptor of AGEs,RAGE)信号通路是糖尿病肾病发生发展的重要一环,在糖尿病肾病中的作用机制主要有激活核转录因子-κB(nuclear factor-κB,NF-κB),刺激产生血管内皮生长因子(vascular endothelial growthfactor,VEGF),刺激转化生长因子-β1(transforming growth factor-β1,TGF-β1)的产生,诱导单核细胞趋化蛋白-1(monocyte chemotactic protein 1,MCP-1)表达的增强,激活P21肾素-血管紧张素导致细胞功能紊乱,激活烟酰胺腺嘌呤二核苷酸磷酸(nicotinamide adenine dinucleotide phosphate,NADPH)氧化酶引起氧化应激等。中医药治疗糖尿病肾病具有整体调节和多通道、多靶点的优势,可通过阻断AGEs-RAGE信号通路改善糖尿病肾病进展。目前研究存在的问题主要有:AGEs-RAGE下游机制复杂,未完全阐明,其与一些关键因子如NF-κB、VGEF、TGF-β1、MCP-1基因的关系还有待进一步研究证实;单味中药和中药复方的活性成分治疗糖尿病肾病的临床研究和动物实验较多,但针对AGEs-RAGE信号通路的研究较少;目前实验大多于体外进行,其机制和作用靶点尚未明确。今后的研究中,需进一步完善实验设计,深入了解AGEs-RAGE信号通路的作用机制,以期为糖尿病肾病的中西医结合治疗提供一定参考。 展开更多
关键词 糖尿病肾病 AGEs-RAGE信号通路 绞股蓝 丹参 山茱萸 黄连 葛根 糖肾方 益糖康 中药降糖复方 益气解毒活络中药复方 化痰补虚益气中药复方
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中国社会福利改革与发展战略:从照顾弱者到普惠全民 被引量:100
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作者 郑功成 《中国人民大学学报》 CSSCI 北大核心 2011年第2期47-60,共14页
社会福利是我国社会保障体系的重要组成部分,但一直滞后于社会保险、社会救助的发展,并存在着体系残缺、多元分割、制度紊乱、功能异化等缺陷,越来越不适应人口老龄化与社会发展所带来的城乡居民福利需求全面升级的需要。因此,国家应当... 社会福利是我国社会保障体系的重要组成部分,但一直滞后于社会保险、社会救助的发展,并存在着体系残缺、多元分割、制度紊乱、功能异化等缺陷,越来越不适应人口老龄化与社会发展所带来的城乡居民福利需求全面升级的需要。因此,国家应当全面促进社会福利事业的发展,并在政府的主导下,通过建立项目完整、保障功能强、社会化运行、多层次发展的社会福利体系,全面满足城乡居民的社会福利需求,让全体人民真正实现生有体面、死有尊严,实现中国社会福利体系从照顾弱者向普惠全民的转变。 展开更多
关键词 社会福利 发展战略 照顾弱者 普惠全民
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温针灸配合耳穴贴压调节阳虚型失眠患者神经递质临床观察 被引量:77
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作者 杨金亮 张蓉 +2 位作者 杜磊 杨云霜 刘晓晨 《中国针灸》 CAS CSCD 北大核心 2014年第12期1165-1168,共4页
目的:通过对失眠患者脑内神经递质水平的监测,评价温针灸配合耳穴贴压治疗失眠的作用机制及疗效。方法:将130例失眠患者随机分为观察组、对照组,每组65例。观察组以温阳益气为治则,针刺心俞、脾俞、肾俞、腰阳关、百会、内关、神门,... 目的:通过对失眠患者脑内神经递质水平的监测,评价温针灸配合耳穴贴压治疗失眠的作用机制及疗效。方法:将130例失眠患者随机分为观察组、对照组,每组65例。观察组以温阳益气为治则,针刺心俞、脾俞、肾俞、腰阳关、百会、内关、神门,并于心俞、脾俞、肾俞、腰阳关行温针灸,每日1次;对照组采用口服艾司唑仑片0.5~1mg,晚上临睡觉前30min服用,两组均14天为一疗程,治疗2个疗程。通过脑电超慢涨落分析技术,观察两组治疗前后睡眠质量以及脑内神经递质水平的变化情况,并比较两组疗效。结果:观察组总有效率为83.1%(54/65),对照组为87.7%(57/65),两组疗效相当(P〉0.05)。观察组治疗后5-羟色胺(5-HT),γ-氨基丁酸、谷氨酸比值(GABA/Glu)均较治疗前增加(P〈0.05,P〈0.01),去甲肾上腺素(NE)较治疗前减少(P〈0.05),而对照组各项指标治疗前后差异无统计学意义(均P〉0.05);观察组对5-HT、GABA/Glu的调节作用优于对照组(均P〈0.05)。结论:温针灸配合耳穴贴压温阳益气法能有效改善阳虚型失眠患者脑内神经递质,从根本上改善睡眠质量。 展开更多
关键词 失眠症 温阳益气 针灸疗法 耳穴贴压 神经递质
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3种不同中医治则治疗少弱精子症患者的随机对照观察 被引量:61
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作者 郭军 王福 +5 位作者 张强 耿强 余国今 赵家有 高庆和 宋春生 《中国中西医结合杂志》 CAS CSCD 北大核心 2013年第9期1170-1173,共4页
目的评价3种不同中医治则治疗男性不育症(少弱精子症)患者的疗效及安全性。方法 128例男性不育症患者中医辨证分别为肾精亏虚证、脾肾两虚证、肾虚血瘀证。按分层随机以3∶1比例分为中药组(96例)与西药对照组(32例),中药组分别采用补益... 目的评价3种不同中医治则治疗男性不育症(少弱精子症)患者的疗效及安全性。方法 128例男性不育症患者中医辨证分别为肾精亏虚证、脾肾两虚证、肾虚血瘀证。按分层随机以3∶1比例分为中药组(96例)与西药对照组(32例),中药组分别采用补益肾气、补肾健脾、补肾活血等中药治疗;西药对照组采用克罗米芬(25mg/次,每天1次)治疗,两组连续服药3个月为1个疗程,共观察1个疗程。观察精液参数、怀孕率及不良反应等指标。结果 2组共脱落24例,其中中药组脱落17例(肾虚血瘀证9例,脾肾两虚证5例,肾精亏虚证3例),西药对照组脱落7例;与治疗前比较,2组治疗3个月时,精液量改善差异无统计学意义(P>0.05);而精液密度、A级精子、A+B级精子、1h活动率改善差异有统计学意义(P<0.05);其中肾虚血瘀证改善最明显,脾肾两虚证、肾精亏虚证次之,西药对照组改善最弱。治疗3个月组间比较,2组改善精液量、精液密度、A级精子、1h活动率差异均无统计学意义(P>0.05);而在改善A+B级精子方面,肾虚血瘀证提高明显,与其他两证及西药对照组比较,差异均有统计学意义(P<0.05,P<0.01)。治疗期间2组均未出现明显的不良反应。结论补肾活血法在提高男性不育症(少弱精子症)精子密度,改善精子的活动方面优于补肾健脾及补益肾气法。 展开更多
关键词 补肾活血 补肾健脾 补益肾气 少弱精子症 随机对照观察
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