The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-su...The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-sufficiency, and by “Special Nature”, gravitational and two other properties of matter, “tied” to the “Eternal Movement” and completely dependent on it. Carriers of key properties of a “Special Nature” have been established: “0”-DE particles and “3”-DM particles (UDM). The unity of their inherent “motionally-gravitational” properties and the peculiarity of the relationship between “motion” and “gravity” are revealed: the higher the intensity of “Eternal Motion”, the stronger the gravitational properties of matter are manifested (and vice versa). The relationship of “time” with the “vibration frequency” and the “mass” of photons with the “degree of bonding and deformation properties of the field” is shown. The maximum level of gravity has been determined, which allows Nature to successfully create the Universe: such a landmark is the proximity to the property of the Primary Source—the “pure graviton” of the OSP space, the most powerful “motionally-gravitational” particle of the Universe. The reasons for the emergence of such an identity of the gravitational properties of particles with the indicators of a “pure graviton” are established: for “0”-DE particles, this is the acquisition of the function of “freedom of movement”;for “3”-DM particles (UDM), the creation of a special structure—a “double field” (“Main” and “Small”). The presence in the “double field” of specific “tools” for the creation of the worlds of the Universe—gravitational “waves” gives rise to impulses (shocks) of varying intensity and shape. A list of functions performed by “waves” in the “Main” and “Small” fields has been compiled. The specific conditions for the formation of “UDM Streams”, their transform展开更多
Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness worldwide.There is currently no cure for vision loss in glaucoma because retinal ganglion cells do not r...Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness worldwide.There is currently no cure for vision loss in glaucoma because retinal ganglion cells do not regenerate and are not replaced after injury.Human stem cell-derived retinal ganglion cell transplant is a potential therapeutic strategy for retinal ganglion cell degenerative diseases.In this review,we first discuss a 2D protocol for retinal ganglion cell differentiation from human stem cell culture,including a rapid protocol that can generate retinal ganglion cells in less than two weeks and focus on their transplantation outcomes.Next,we discuss using 3D retinal organoids for retinal ganglion cell transplantation,comparing cell suspensions and clusters.This review provides insight into current knowledge on human stem cell-derived retinal ganglion cell differentiation and transplantation,with an impact on the field of regenerative medicine and especially retinal ganglion cell degenerative diseases such as glaucoma and other optic neuropathies.展开更多
Taking the Big Bang as an established fact, the question inevitably arises about what exactly caused it, in what environment could it have happened and what happened before it. The developed approach allows us to shed...Taking the Big Bang as an established fact, the question inevitably arises about what exactly caused it, in what environment could it have happened and what happened before it. The developed approach allows us to shed light on many raised questions and to establish what universal laws and structures formed what happened before the Big Bang, to understand its cause and the dynamic processes that led to it. This required a radical revision of many views, giving them a new meaning and content. This approach has led to a consistent and conceptually new understanding of these phenomena, which allowed correctly formulate questions to which there are still no clear answers. Based on this formulation of the problem, we came to new ideas about the nature of Dark energy, Dark matter and the region of their birth, formulated and described the mechanism of the formation of worlds and their hierarchy on the other side of the Big Bang and the mechanism of this explosion itself. The Primary Parent Particle was introduced into the concept, which was the basis of everything and is the carrier of the fundamental Primary space introduced by us, which had at least two phase states. This particle consists of Beginnings united in the form of Borromeo rings. This made it possible to calculate the structure and primary spectrum of elementary particles that arose on the other side of the Big Bang, the mechanisms of their formation and the resulting fundamental interactions that lead to the existence of vortices before the Big Bang;the mechanisms of the birth of multiple universes and much more are also considered. The concept of the “cosmic genetic code" is introduced, the characteristics and mechanism of its formation before the Big Bang are presented.展开更多
A kind of quick, efficient and season-free inducing embryoid and multiple shoot clumps system from shoot tip meristems that derived from elite inbreds of maize was established. The herbicide-resistant gene a/s (coding...A kind of quick, efficient and season-free inducing embryoid and multiple shoot clumps system from shoot tip meristems that derived from elite inbreds of maize was established. The herbicide-resistant gene a/s (coding Acetolactate synthase) isolated from a mutant of Arabidopsis thaliana was transferred to tissue pieces of maize multiple shoot clumps by microprojectile bombardment. Herbicide-resistant tissue and regenerants were obtained through selections with herbicide chlorsulfuron. PCR analysis and Southern blot hybridization indicated that gene a/s has been transferred to some regenerants. The test of spraying chlorsulfuron displayed that the transgenic plantlets and R1 plants had favorable herbicide-resistant trait. We have established a new genotype-free system of maize which could rapidly and efficiently produce large quantities of transgenic plantlets.展开更多
This paper introduces the design and implementation of BCL-3, a high per- formance low-level communication software running on a cluster of SMPs (CLUMPS) called DAWNING-3000. BCL-3 provides flexible and sufficient fun...This paper introduces the design and implementation of BCL-3, a high per- formance low-level communication software running on a cluster of SMPs (CLUMPS) called DAWNING-3000. BCL-3 provides flexible and sufficient functionality to fulfill the commu- nication requirements of fundamental system software developed for DAWNING-3000 while guaranteeing security, scalability, and reliability. Important features of BCL-3 are presented in the paper, including special support for SMP and heterogeneous network environment, semi- user-level communication, reliable and ordered data transfer and scalable flow control. The performance evaluation of BCL-3 over Myrinet is also given.展开更多
Here we present the study on chemical properties of massive star forming clumps using N2H^+(1-0),H^13CO+(1-0),HCN(1-0)and HN^13C(1-0)data from the literature[Astron.Astrophys.563,A97(2014)].We found that abundances of...Here we present the study on chemical properties of massive star forming clumps using N2H^+(1-0),H^13CO+(1-0),HCN(1-0)and HN^13C(1-0)data from the literature[Astron.Astrophys.563,A97(2014)].We found that abundances of H^13CO+ and HN^13C are a ected by H2 column densities.As the median values of these two abundances increase by nearly 10 times from stages A to B,H^13CO+and HN^13C are suitable for tracing the evolution of massive star forming clumps.The order of rapidity in growth of abundances of all the four studied molecules from stages A to B,is H^13CO^+,HCN,HN^13C,and N2H^+,from the highest to the lowest.Our results suggest that the observing optically thin molecular lines with high angular resolution are necessary to study the chemical evolution of massive star forming clumps.展开更多
文摘The article hypothesizes that DE and DM (UCM) are a “Form of Motion of a Special Nature”, where “Form of Motion” means “Eternal Motion” as the power of dynamics of different levels and varying degrees of self-sufficiency, and by “Special Nature”, gravitational and two other properties of matter, “tied” to the “Eternal Movement” and completely dependent on it. Carriers of key properties of a “Special Nature” have been established: “0”-DE particles and “3”-DM particles (UDM). The unity of their inherent “motionally-gravitational” properties and the peculiarity of the relationship between “motion” and “gravity” are revealed: the higher the intensity of “Eternal Motion”, the stronger the gravitational properties of matter are manifested (and vice versa). The relationship of “time” with the “vibration frequency” and the “mass” of photons with the “degree of bonding and deformation properties of the field” is shown. The maximum level of gravity has been determined, which allows Nature to successfully create the Universe: such a landmark is the proximity to the property of the Primary Source—the “pure graviton” of the OSP space, the most powerful “motionally-gravitational” particle of the Universe. The reasons for the emergence of such an identity of the gravitational properties of particles with the indicators of a “pure graviton” are established: for “0”-DE particles, this is the acquisition of the function of “freedom of movement”;for “3”-DM particles (UDM), the creation of a special structure—a “double field” (“Main” and “Small”). The presence in the “double field” of specific “tools” for the creation of the worlds of the Universe—gravitational “waves” gives rise to impulses (shocks) of varying intensity and shape. A list of functions performed by “waves” in the “Main” and “Small” fields has been compiled. The specific conditions for the formation of “UDM Streams”, their transform
基金supported by NIH Core Grants P30-EY008098the Eye and Ear Foundation of Pittsburghunrestricted grants from Research to Prevent Blindness,New York,NY,USA(to KCC)。
文摘Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness worldwide.There is currently no cure for vision loss in glaucoma because retinal ganglion cells do not regenerate and are not replaced after injury.Human stem cell-derived retinal ganglion cell transplant is a potential therapeutic strategy for retinal ganglion cell degenerative diseases.In this review,we first discuss a 2D protocol for retinal ganglion cell differentiation from human stem cell culture,including a rapid protocol that can generate retinal ganglion cells in less than two weeks and focus on their transplantation outcomes.Next,we discuss using 3D retinal organoids for retinal ganglion cell transplantation,comparing cell suspensions and clusters.This review provides insight into current knowledge on human stem cell-derived retinal ganglion cell differentiation and transplantation,with an impact on the field of regenerative medicine and especially retinal ganglion cell degenerative diseases such as glaucoma and other optic neuropathies.
文摘Taking the Big Bang as an established fact, the question inevitably arises about what exactly caused it, in what environment could it have happened and what happened before it. The developed approach allows us to shed light on many raised questions and to establish what universal laws and structures formed what happened before the Big Bang, to understand its cause and the dynamic processes that led to it. This required a radical revision of many views, giving them a new meaning and content. This approach has led to a consistent and conceptually new understanding of these phenomena, which allowed correctly formulate questions to which there are still no clear answers. Based on this formulation of the problem, we came to new ideas about the nature of Dark energy, Dark matter and the region of their birth, formulated and described the mechanism of the formation of worlds and their hierarchy on the other side of the Big Bang and the mechanism of this explosion itself. The Primary Parent Particle was introduced into the concept, which was the basis of everything and is the carrier of the fundamental Primary space introduced by us, which had at least two phase states. This particle consists of Beginnings united in the form of Borromeo rings. This made it possible to calculate the structure and primary spectrum of elementary particles that arose on the other side of the Big Bang, the mechanisms of their formation and the resulting fundamental interactions that lead to the existence of vortices before the Big Bang;the mechanisms of the birth of multiple universes and much more are also considered. The concept of the “cosmic genetic code" is introduced, the characteristics and mechanism of its formation before the Big Bang are presented.
基金This work was supported by the National "863" Project and Key Items of Scientific Technique Research from the Ministry of Education of China.
文摘A kind of quick, efficient and season-free inducing embryoid and multiple shoot clumps system from shoot tip meristems that derived from elite inbreds of maize was established. The herbicide-resistant gene a/s (coding Acetolactate synthase) isolated from a mutant of Arabidopsis thaliana was transferred to tissue pieces of maize multiple shoot clumps by microprojectile bombardment. Herbicide-resistant tissue and regenerants were obtained through selections with herbicide chlorsulfuron. PCR analysis and Southern blot hybridization indicated that gene a/s has been transferred to some regenerants. The test of spraying chlorsulfuron displayed that the transgenic plantlets and R1 plants had favorable herbicide-resistant trait. We have established a new genotype-free system of maize which could rapidly and efficiently produce large quantities of transgenic plantlets.
基金This work is supported by the National '863' High-Tech Programme of China (No.863-306-ZD01-01).
文摘This paper introduces the design and implementation of BCL-3, a high per- formance low-level communication software running on a cluster of SMPs (CLUMPS) called DAWNING-3000. BCL-3 provides flexible and sufficient functionality to fulfill the commu- nication requirements of fundamental system software developed for DAWNING-3000 while guaranteeing security, scalability, and reliability. Important features of BCL-3 are presented in the paper, including special support for SMP and heterogeneous network environment, semi- user-level communication, reliable and ordered data transfer and scalable flow control. The performance evaluation of BCL-3 over Myrinet is also given.
基金the Open Program of the Key Laboratory of Xinjiang Uygur Autonomous Region(No.2019D04023)the National Natural Science foundation of China(No.11973076)+1 种基金the National Natural Science foundation of China(No.11433008,No.11603063,No.11703074 and No.11703073)the CAS"Light of West China"Program(No.2018-XBQNXZ-B-024,No.2016-QNXZB-23,and No.2016-QNXZ-B-22).
文摘Here we present the study on chemical properties of massive star forming clumps using N2H^+(1-0),H^13CO+(1-0),HCN(1-0)and HN^13C(1-0)data from the literature[Astron.Astrophys.563,A97(2014)].We found that abundances of H^13CO+ and HN^13C are a ected by H2 column densities.As the median values of these two abundances increase by nearly 10 times from stages A to B,H^13CO+and HN^13C are suitable for tracing the evolution of massive star forming clumps.The order of rapidity in growth of abundances of all the four studied molecules from stages A to B,is H^13CO^+,HCN,HN^13C,and N2H^+,from the highest to the lowest.Our results suggest that the observing optically thin molecular lines with high angular resolution are necessary to study the chemical evolution of massive star forming clumps.
