A kind of hydroxyapatite (HA) high-porous ceramic (HPC) which is used as pharmaceutical carrier for spinal tuberculosis treating is investigated, the structure of HPC is analyzed and physicochemical properties are det...A kind of hydroxyapatite (HA) high-porous ceramic (HPC) which is used as pharmaceutical carrier for spinal tuberculosis treating is investigated, the structure of HPC is analyzed and physicochemical properties are determined. Experiments and clinical application show that when HPC carrying antituberculosis drug was imbedded in the tuberculosis focus, the drug in effective concentration can continuously be released for 27 weeks, also, the drug concentration achieves high local level but low systematic level, thus the curative effect can distinctly enhanced.展开更多
文摘A kind of hydroxyapatite (HA) high-porous ceramic (HPC) which is used as pharmaceutical carrier for spinal tuberculosis treating is investigated, the structure of HPC is analyzed and physicochemical properties are determined. Experiments and clinical application show that when HPC carrying antituberculosis drug was imbedded in the tuberculosis focus, the drug in effective concentration can continuously be released for 27 weeks, also, the drug concentration achieves high local level but low systematic level, thus the curative effect can distinctly enhanced.
