Organic electrochemistry has a rich history in organic synthesis and has been considered as a promising alternative to traditional chemical oxidants and reductants because it obviates the use of stoichiometric amount ...Organic electrochemistry has a rich history in organic synthesis and has been considered as a promising alternative to traditional chemical oxidants and reductants because it obviates the use of stoichiometric amount of dangerous and toxic reagents. In particular, the electrochemical C-H bonds functionalization is one of the most desirable approaches for the construction of carbon-carbon （C-C） and carbon-heteroatom （C-X） bonds. This review summarizes the substantial progress made in the last few years in C-H functionalization via organic electrochemistry. It is divided into sections on C-C, C-N, C-O, C-S, C-Halogen and C-P bond formation.展开更多
Aromatic ketones are directly alkylated at a position with primary alcohols at 110 ℃ in the presence of catalytic amount of KOH and [Cp＊lrC12]2 （Cp＊=pentamethylcyclopentadienyl） catalyst. The reaction is carried ...Aromatic ketones are directly alkylated at a position with primary alcohols at 110 ℃ in the presence of catalytic amount of KOH and [Cp＊lrC12]2 （Cp＊=pentamethylcyclopentadienyl） catalyst. The reaction is carried out in the absence of any solvent or additive, which generates only water as the byproduct in theory. It is very efficient and generally completed in 10 min in good isolated yields. The reaction is believed to undergo successive hydrogen transfer and cross aldol condensation processes.展开更多
文摘Organic electrochemistry has a rich history in organic synthesis and has been considered as a promising alternative to traditional chemical oxidants and reductants because it obviates the use of stoichiometric amount of dangerous and toxic reagents. In particular, the electrochemical C-H bonds functionalization is one of the most desirable approaches for the construction of carbon-carbon （C-C） and carbon-heteroatom （C-X） bonds. This review summarizes the substantial progress made in the last few years in C-H functionalization via organic electrochemistry. It is divided into sections on C-C, C-N, C-O, C-S, C-Halogen and C-P bond formation.
文摘Aromatic ketones are directly alkylated at a position with primary alcohols at 110 ℃ in the presence of catalytic amount of KOH and [Cp＊lrC12]2 （Cp＊=pentamethylcyclopentadienyl） catalyst. The reaction is carried out in the absence of any solvent or additive, which generates only water as the byproduct in theory. It is very efficient and generally completed in 10 min in good isolated yields. The reaction is believed to undergo successive hydrogen transfer and cross aldol condensation processes.
