Objective:To observe the lipid-lowering effect of different transdermal absorption enhancers applied to the herbal cake-partitioned moxibustion in hyperlipidemia model rabbits,and to explore the possible mechanism.Met...Objective:To observe the lipid-lowering effect of different transdermal absorption enhancers applied to the herbal cake-partitioned moxibustion in hyperlipidemia model rabbits,and to explore the possible mechanism.Methods:Forty New-Zea I a nd rabbits were ran domly divided into 5 groups using the ran dom nu mber table method,with 8 rats in each group.Rabbits in the blank group were fed routinely with normal diet;rabbits in the other groups were fed with high-fat diet for 12 weeks to establish the hyperlipidemia model.Rabbits in the blank and the model groups were not treated.After the model was prepared,rabbits in the non-transdermal absorption enhancer group received herbal cake-partitioned moxibustion without transdermal absorption enhancer;rabbits in the laurocapram group and the borneol group received herbal cake-partitioned moxibustion with laurocapram or borneol respectively.After 4 weeks of treatment,serum was collected for enzyme-linked immunosorbent assay(ELISA),and the liver tissues were isolated for imm uno histochemistry,qua ntitative polymerase chain reactio n(qPCR)and Western-blotting(WB)detecti on.Results:Serum ELISA results showed that leptin was significantly decreased in the model group compared with the blank group(P<0.05);compared with the model group,lepti n was significa ntly in creased in the non-tran sdermal absorpti on enhanee。the laurocapram and the borneol groups(all P<0.05);compared with the non-transdermal absorption enhancer group,leptin was significantly increased in the laurocapram group and the borneol group(both P<0.05);there was no significant differenee in leptin between the laurocapram and the borneol groups(P>0.05).The qPCR results of rabbit liver tissues showed that the mRNA expressions of leptin,Janus kinase 2(JAK2)and signal transducer and activator of transcription 3(STOT3)in the model group were significantly lower than those in the blank group(all P<0.05);compared with the model group,the mRNA expressions of leptin,leptin receptor(LR),JAK2 and S1AT3 in the non-transde展开更多
Studies carried out in the delta and the lower valley have demonstrated, through ethnobotanical surveys, the importance of the species Nymphaea lotus L. and Nymphaea micrantha Guill. et Perr in the diet. The seeds are...Studies carried out in the delta and the lower valley have demonstrated, through ethnobotanical surveys, the importance of the species Nymphaea lotus L. and Nymphaea micrantha Guill. et Perr in the diet. The seeds are used in food and pharmacopoeia with a good appreciation by the indigenous population, especially in the diet of diabetics. However, studies on their biochemical aspects are still very rare in the literature. It is for this reason that this study was conducted to gather useful scientific information to allow a better appreciation of the pharmacological potentialities of these seeds. To do so, seeds were collected in ponds, tributaries of the Senegal River, dried in the shade, and divided into three different batches: a batch of red seeds of N. lotus, a batch of black seeds of N. lotus, and a batch of seeds of N. micrantha. Chemical screening, tannin, flavonoid, and polyphenol assays as well as antioxidant power of the seeds were carried out according to official standard methods. The results obtained in the qualitative analysis showed the presence of a high quantity of tannins, total phenols, flavonoids, and alkaloids, as well as a lower quantity of cardiac glycosides and the absence of anthracene compounds and saponosides in the seeds. The assay showed that Tannins are the highest (38.118 ± 0.021 to 118.132 ± 0.034 mg EAT/g DM) followed by flavonoids (24.057 ± 0.113 to 31.970 ± 0.087 mg EC/g DM) and polyphenols which are the lowest (0.544 ± 0.054 to 1.955 ± 0.120 mg EAG/g DM). In addition, these seeds have a high antioxidant power with high inhibition percentages, ranging from 83.92% ± 1.40% to 87.67% ± 0.16%. The promotion of their consumption could thus have a positive impact on the health of the populations of the Senegal River valley.展开更多
In this paper, a process modeling and related optimizing control for nonuniformly sampled （NUS） systems are addressed. By using a proposed nonuniform integration filter and subspace method estimation, an identificat...In this paper, a process modeling and related optimizing control for nonuniformly sampled （NUS） systems are addressed. By using a proposed nonuniform integration filter and subspace method estimation, an identification method of NUS systems is developed, based on which either an output soft sensor or a hidden state estimator is developed. The optimizing control is implemented by replacing the sparsely-mea- sured/immeasurable variable with the estimated one. Examples of optimizing control problem are given. The proposed optimizing control strategy in the simulation examples is verified to be very effeetive.展开更多
Cucurbitaceae family contains important economic and medical crops, they can be divided into two categories according to the worldwide consumption, use, and production. The Cucurbit Popular Crops (CuPoC) are comprised...Cucurbitaceae family contains important economic and medical crops, they can be divided into two categories according to the worldwide consumption, use, and production. The Cucurbit Popular Crops (CuPoC) are comprised of cucumber, the Cucurbita group (pumpkin and squash), melon and watermelon. On the other hand, Neglected and Underutilized Cucurbit Species (NUCuS) group has been used as food sources, medicinal properties and elements in the elaboration of different types of items. The NUCuS is represented in this review work by bitter gourd, bottle gourd, chayote, ridge gourd, and snake gourd, which are recognized mainly in Asia. The center of origin of the majority of NUCuS was proposed to be in the Old World. In contrast, the origin of chayote or Sechiumedule (Jacq.) Sw. was suggested in the New World, precisely in Mesoamerican region based on linguistic uses and distribution of wild relatives. The environmental factors along with artificial selection, production systems and traditional knowledge have been influenced the evolutionary history of NUCuS, Infraspecific variation of chayote has been reported in Mexico over-described varietal groups. These descriptors were determined based on biochemical and morpho-structural traits;however, cytogenetic analyses are scarce. Specifically, chromosome and nuclear content analyses are important to support botanical groups, analyze artificial selection history, developing breeding and conservation programs. The present review paper discusses agronomic and evolutionary importance based on cytological evidence in NUCuS, mainly in the prominent chayote;with the perspective to prompt breeding, conservation, cytology, structural and functional genomics research for its sustainable utilization.展开更多
文摘Objective:To observe the lipid-lowering effect of different transdermal absorption enhancers applied to the herbal cake-partitioned moxibustion in hyperlipidemia model rabbits,and to explore the possible mechanism.Methods:Forty New-Zea I a nd rabbits were ran domly divided into 5 groups using the ran dom nu mber table method,with 8 rats in each group.Rabbits in the blank group were fed routinely with normal diet;rabbits in the other groups were fed with high-fat diet for 12 weeks to establish the hyperlipidemia model.Rabbits in the blank and the model groups were not treated.After the model was prepared,rabbits in the non-transdermal absorption enhancer group received herbal cake-partitioned moxibustion without transdermal absorption enhancer;rabbits in the laurocapram group and the borneol group received herbal cake-partitioned moxibustion with laurocapram or borneol respectively.After 4 weeks of treatment,serum was collected for enzyme-linked immunosorbent assay(ELISA),and the liver tissues were isolated for imm uno histochemistry,qua ntitative polymerase chain reactio n(qPCR)and Western-blotting(WB)detecti on.Results:Serum ELISA results showed that leptin was significantly decreased in the model group compared with the blank group(P<0.05);compared with the model group,lepti n was significa ntly in creased in the non-tran sdermal absorpti on enhanee。the laurocapram and the borneol groups(all P<0.05);compared with the non-transdermal absorption enhancer group,leptin was significantly increased in the laurocapram group and the borneol group(both P<0.05);there was no significant differenee in leptin between the laurocapram and the borneol groups(P>0.05).The qPCR results of rabbit liver tissues showed that the mRNA expressions of leptin,Janus kinase 2(JAK2)and signal transducer and activator of transcription 3(STOT3)in the model group were significantly lower than those in the blank group(all P<0.05);compared with the model group,the mRNA expressions of leptin,leptin receptor(LR),JAK2 and S1AT3 in the non-transde
文摘Studies carried out in the delta and the lower valley have demonstrated, through ethnobotanical surveys, the importance of the species Nymphaea lotus L. and Nymphaea micrantha Guill. et Perr in the diet. The seeds are used in food and pharmacopoeia with a good appreciation by the indigenous population, especially in the diet of diabetics. However, studies on their biochemical aspects are still very rare in the literature. It is for this reason that this study was conducted to gather useful scientific information to allow a better appreciation of the pharmacological potentialities of these seeds. To do so, seeds were collected in ponds, tributaries of the Senegal River, dried in the shade, and divided into three different batches: a batch of red seeds of N. lotus, a batch of black seeds of N. lotus, and a batch of seeds of N. micrantha. Chemical screening, tannin, flavonoid, and polyphenol assays as well as antioxidant power of the seeds were carried out according to official standard methods. The results obtained in the qualitative analysis showed the presence of a high quantity of tannins, total phenols, flavonoids, and alkaloids, as well as a lower quantity of cardiac glycosides and the absence of anthracene compounds and saponosides in the seeds. The assay showed that Tannins are the highest (38.118 ± 0.021 to 118.132 ± 0.034 mg EAT/g DM) followed by flavonoids (24.057 ± 0.113 to 31.970 ± 0.087 mg EC/g DM) and polyphenols which are the lowest (0.544 ± 0.054 to 1.955 ± 0.120 mg EAG/g DM). In addition, these seeds have a high antioxidant power with high inhibition percentages, ranging from 83.92% ± 1.40% to 87.67% ± 0.16%. The promotion of their consumption could thus have a positive impact on the health of the populations of the Senegal River valley.
基金Supported by the China Postdoctoral Science Foundation Funded Project (No. 20080440386)
文摘In this paper, a process modeling and related optimizing control for nonuniformly sampled （NUS） systems are addressed. By using a proposed nonuniform integration filter and subspace method estimation, an identification method of NUS systems is developed, based on which either an output soft sensor or a hidden state estimator is developed. The optimizing control is implemented by replacing the sparsely-mea- sured/immeasurable variable with the estimated one. Examples of optimizing control problem are given. The proposed optimizing control strategy in the simulation examples is verified to be very effeetive.
基金the Japanese Government(Monbukagakusho)Scholarship.
文摘Cucurbitaceae family contains important economic and medical crops, they can be divided into two categories according to the worldwide consumption, use, and production. The Cucurbit Popular Crops (CuPoC) are comprised of cucumber, the Cucurbita group (pumpkin and squash), melon and watermelon. On the other hand, Neglected and Underutilized Cucurbit Species (NUCuS) group has been used as food sources, medicinal properties and elements in the elaboration of different types of items. The NUCuS is represented in this review work by bitter gourd, bottle gourd, chayote, ridge gourd, and snake gourd, which are recognized mainly in Asia. The center of origin of the majority of NUCuS was proposed to be in the Old World. In contrast, the origin of chayote or Sechiumedule (Jacq.) Sw. was suggested in the New World, precisely in Mesoamerican region based on linguistic uses and distribution of wild relatives. The environmental factors along with artificial selection, production systems and traditional knowledge have been influenced the evolutionary history of NUCuS, Infraspecific variation of chayote has been reported in Mexico over-described varietal groups. These descriptors were determined based on biochemical and morpho-structural traits;however, cytogenetic analyses are scarce. Specifically, chromosome and nuclear content analyses are important to support botanical groups, analyze artificial selection history, developing breeding and conservation programs. The present review paper discusses agronomic and evolutionary importance based on cytological evidence in NUCuS, mainly in the prominent chayote;with the perspective to prompt breeding, conservation, cytology, structural and functional genomics research for its sustainable utilization.
