目的探究宝石能谱CT(GSI)定量参数在鉴别脊柱肺癌骨转移瘤和多发性骨髓瘤(multiple myeloma,MM)溶骨性病灶的应用潜力。方法应用能谱CT扫描技术,对病灶感兴趣区在各单能量图像下的CT值及能谱曲线斜率进行两样本的Mann Whitney U检验的...目的探究宝石能谱CT(GSI)定量参数在鉴别脊柱肺癌骨转移瘤和多发性骨髓瘤(multiple myeloma,MM)溶骨性病灶的应用潜力。方法应用能谱CT扫描技术,对病灶感兴趣区在各单能量图像下的CT值及能谱曲线斜率进行两样本的Mann Whitney U检验的统计学分析。结果平扫后肺癌骨转移病灶在40~90 ke V对应的CT值的中位数高于骨髓瘤病灶,差异有统计学意义(P<0.05);平扫后肺癌转移灶能谱曲线斜率(40~90 ke V为参考点)的中位数大于骨髓瘤病灶,差异有统计学意义(P<0.05);平扫后肺癌骨转移病灶与骨髓瘤病灶在95~140 ke V对应的CT值的中位数相互比较,差异无统计学意义(P>0.05)。结论能谱CT能够准确测量两组病灶单能量下CT值及能谱曲线斜率,在两类疾病的鉴别诊断中具有一定的应用价值。展开更多
Objective: We aim to explore the relationship between fatty liver and the severity of acute pancreatitis. Methods: The data of 128 patients with acute pancreatitis in the Xiaogan Central Hospital of Hubei from October...Objective: We aim to explore the relationship between fatty liver and the severity of acute pancreatitis. Methods: The data of 128 patients with acute pancreatitis in the Xiaogan Central Hospital of Hubei from October 2016 to October 2017 were retrospectively analyzed. Clinical data of patients with fatty liver and non-fatty liver were statistically analyzed, the CT value of the liver and spleen was measure, and fatty liver was defined as mean L/SCT value Results: Among 128 patients, fatty liver was found in 56 (43.8%) and nonfatty liver in 72 (56.2%). Compared with patients with non fatty liver disease, the severity of pancreatitis, blood triglyceride and C reactive protein levels were higher in fatty liver patients, higher proportion of patients with local complications and persistent organ failure. Conclusion: Fatty liver has a greater impact on the severity of acute pancreatitis. It is possible to be an indicator of the severity of acute pancreatitis.展开更多
目的应用meta分析对腰椎CT值诊断骨质疏松症进行评价。方法检索包括PubMed、Cochrane Library、Web of Science、中国知网、万方及维普等中外数据库中关于腰椎CT值诊断骨质疏松患者的相关研究并提取基本资料和四格表数据(检索时限从建库...目的应用meta分析对腰椎CT值诊断骨质疏松症进行评价。方法检索包括PubMed、Cochrane Library、Web of Science、中国知网、万方及维普等中外数据库中关于腰椎CT值诊断骨质疏松患者的相关研究并提取基本资料和四格表数据(检索时限从建库至2021年12月),利用诊断试验质量评价工具(QUADAS-2)评价纳入研究的偏倚风险。采用Review Manager 5.4、Meta-Disc 1.4进行meta分析。结果本文总共纳入13篇文献,腰椎CT值诊断骨质疏松症按照椎体不同分为L1、L2、L3、L4、L5和L1-L4椎体平均值6个组,因L5和L1-L4椎体纳入的数据各只有一组,因此未进行效应量合并。L1其汇总敏感度为0.75(95%CI:0.72-0.77),汇总特异度为0.72(95%CI:0.70-0.73),拟合SROC曲线下面积为0.8126。L2汇总敏感度为0.73(95%CI:0.70-0.77),汇总特异度为0.75(95%CI:0.73-0.77),拟合SROC曲线下面积为0.8010。L3汇总敏感度为0.78(95%CI:0.75-0.81),汇总特异度为0.72(95%CI:0.70-0.74),拟合SROC曲线下面积为0.7935。L4汇总敏感度为0.76(95%CI:0.73-0.79),汇总特异度为0.73(95%CI:0.70-0.75)。结论腰椎CT值在人群中进行骨质疏松症的筛查方面具有一定意义,而其确诊骨质疏松症的能力不佳,确诊还需结合其他检查结果综合分析。展开更多
文摘目的探究宝石能谱CT(GSI)定量参数在鉴别脊柱肺癌骨转移瘤和多发性骨髓瘤(multiple myeloma,MM)溶骨性病灶的应用潜力。方法应用能谱CT扫描技术,对病灶感兴趣区在各单能量图像下的CT值及能谱曲线斜率进行两样本的Mann Whitney U检验的统计学分析。结果平扫后肺癌骨转移病灶在40~90 ke V对应的CT值的中位数高于骨髓瘤病灶,差异有统计学意义(P<0.05);平扫后肺癌转移灶能谱曲线斜率(40~90 ke V为参考点)的中位数大于骨髓瘤病灶,差异有统计学意义(P<0.05);平扫后肺癌骨转移病灶与骨髓瘤病灶在95~140 ke V对应的CT值的中位数相互比较,差异无统计学意义(P>0.05)。结论能谱CT能够准确测量两组病灶单能量下CT值及能谱曲线斜率,在两类疾病的鉴别诊断中具有一定的应用价值。
文摘Objective: We aim to explore the relationship between fatty liver and the severity of acute pancreatitis. Methods: The data of 128 patients with acute pancreatitis in the Xiaogan Central Hospital of Hubei from October 2016 to October 2017 were retrospectively analyzed. Clinical data of patients with fatty liver and non-fatty liver were statistically analyzed, the CT value of the liver and spleen was measure, and fatty liver was defined as mean L/SCT value Results: Among 128 patients, fatty liver was found in 56 (43.8%) and nonfatty liver in 72 (56.2%). Compared with patients with non fatty liver disease, the severity of pancreatitis, blood triglyceride and C reactive protein levels were higher in fatty liver patients, higher proportion of patients with local complications and persistent organ failure. Conclusion: Fatty liver has a greater impact on the severity of acute pancreatitis. It is possible to be an indicator of the severity of acute pancreatitis.
