Background:Previous studies have reported associations of specific maternal and paternal lifestyle factors with offspring’s cognitive development during early childhood.This study aimed to investigate the prospective...Background:Previous studies have reported associations of specific maternal and paternal lifestyle factors with offspring’s cognitive development during early childhood.This study aimed to investigate the prospective associations between overall parental lifestyle and offspring’s cognitive performance during adolescence and young adulthood in China.Methods:We included 2531 adolescents aged 10-15 years at baseline in 2010 from the China Family Panel Studies.A healthy parental lifestyle score(ranged 0-5)was constructed based on the following five modifiable lifestyle factors:Smoking,drinking,exercise,sleep,and diet.Generalized estimating equation models were used to examine the association between baseline parental healthy lifestyle scores and offspring’s fluid and crystallized intelligence in subsequent years(2012,2014,2016,and 2018).Results:Offspring in the top tertile of parental healthy lifestyle scores performed better in overall fluid intelligence(multivariable-adjusted β=0.53,95%confidence interval[CI]:0.29-0.77)and overall crystallized intelligence(multivariable-adjusted β=0.35,95%CI:0.16-0.54)than those in the bottom tertile of parental healthy lifestyle scores.The results were similar after further adjustment for the offspring’s healthy lifestyle scores and persisted across the subgroups of parental socioeconomic status.Additionally,maternal and paternal healthy lifestyle scores were independently associated with better offspring’s cognitive performance,with significant contribution observed for paternal never-smoking,weekly exercise,and diversified diet.When both parents and offspring adhered to a healthier lifestyle,we observed the highest level of the offspring’s overall crystallized intelligence.Conclusions:Our study indicates that parental adherence to a healthier lifestyle is associated with significantly better offspring’s cognitive performance during adolescence and early adulthood,regardless of socioeconomic status.These findings highlight the potential cognitive benefits of promo展开更多
Organic photovoltaic semiconductors have made significant progress and have promising application prospects after decades of development.When compared with traditional semiconductors,the solution method for preparing ...Organic photovoltaic semiconductors have made significant progress and have promising application prospects after decades of development.When compared with traditional semiconductors,the solution method for preparing photovoltaic semiconductors shows the advantages of low cost and convenient preparation.However,because of the extremely poor solubility of the polymers used to prepare semiconductors,toxic solvents must be used when using the solution method,which has significant negative effects on the environment and operators and severely limits its development prospects.Organic nanoparticles(NPs),on the other hand,can avoid these issues.Because NPs are typically water or alcohol-based,no toxic solvents are used.Furthermore,NPs have been used in organic solar cells,hydrogen catalysis,organic light-emitting diodes,and other fields after nearly two decades of development,and their preparation methods have been developed.We describe the preparation,optimization,and application of NPs in photovoltaic semiconductors in this review.展开更多
Amphichoterpenoids A-C(1-3),unprecedented picoline-derived meroterpenoids possessing a pyrano[3,2-c]pyridinyl-g-pyranone scaffold,were characterized from the ascidian-derived fungus Amphichorda felina SYSU-MS7908.Thei...Amphichoterpenoids A-C(1-3),unprecedented picoline-derived meroterpenoids possessing a pyrano[3,2-c]pyridinyl-g-pyranone scaffold,were characterized from the ascidian-derived fungus Amphichorda felina SYSU-MS7908.Their structures were elucidated by spectroscopic methods,X-ray diffraction and electronic circular dichroism(ECD)calculations.A plausible biosynthetic pathway was proposed.The isolated compounds displayed moderate inhibitory activity against acetylcholinesterase with 50%inhibiting concentration(IC_(50))values of 18.8-53.2 mmol/L.展开更多
基金supported by grants from the Zhejiang University Education Foundation Global Partnership Fund(to CZY)the Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province(No.2020E10004).
文摘Background:Previous studies have reported associations of specific maternal and paternal lifestyle factors with offspring’s cognitive development during early childhood.This study aimed to investigate the prospective associations between overall parental lifestyle and offspring’s cognitive performance during adolescence and young adulthood in China.Methods:We included 2531 adolescents aged 10-15 years at baseline in 2010 from the China Family Panel Studies.A healthy parental lifestyle score(ranged 0-5)was constructed based on the following five modifiable lifestyle factors:Smoking,drinking,exercise,sleep,and diet.Generalized estimating equation models were used to examine the association between baseline parental healthy lifestyle scores and offspring’s fluid and crystallized intelligence in subsequent years(2012,2014,2016,and 2018).Results:Offspring in the top tertile of parental healthy lifestyle scores performed better in overall fluid intelligence(multivariable-adjusted β=0.53,95%confidence interval[CI]:0.29-0.77)and overall crystallized intelligence(multivariable-adjusted β=0.35,95%CI:0.16-0.54)than those in the bottom tertile of parental healthy lifestyle scores.The results were similar after further adjustment for the offspring’s healthy lifestyle scores and persisted across the subgroups of parental socioeconomic status.Additionally,maternal and paternal healthy lifestyle scores were independently associated with better offspring’s cognitive performance,with significant contribution observed for paternal never-smoking,weekly exercise,and diversified diet.When both parents and offspring adhered to a healthier lifestyle,we observed the highest level of the offspring’s overall crystallized intelligence.Conclusions:Our study indicates that parental adherence to a healthier lifestyle is associated with significantly better offspring’s cognitive performance during adolescence and early adulthood,regardless of socioeconomic status.These findings highlight the potential cognitive benefits of promo
基金supported by the National Natural Science Foundation of China(Nos.21922505 and 52273245)the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000).
文摘Organic photovoltaic semiconductors have made significant progress and have promising application prospects after decades of development.When compared with traditional semiconductors,the solution method for preparing photovoltaic semiconductors shows the advantages of low cost and convenient preparation.However,because of the extremely poor solubility of the polymers used to prepare semiconductors,toxic solvents must be used when using the solution method,which has significant negative effects on the environment and operators and severely limits its development prospects.Organic nanoparticles(NPs),on the other hand,can avoid these issues.Because NPs are typically water or alcohol-based,no toxic solvents are used.Furthermore,NPs have been used in organic solar cells,hydrogen catalysis,organic light-emitting diodes,and other fields after nearly two decades of development,and their preparation methods have been developed.We describe the preparation,optimization,and application of NPs in photovoltaic semiconductors in this review.
基金the National Natural Science Foundation of China(No.41806155)the Guangdong MEPP Fund(No.GDOE(2019)A21)+2 种基金the National Key R&D Program of China(No.2019YFC0312501)the Natural Science Foundation of Guangdong Province(No.2018A030310304)the Key-Area Research and Development Program of Guangdong Province(No.2020B1111030005)for generous support。
文摘Amphichoterpenoids A-C(1-3),unprecedented picoline-derived meroterpenoids possessing a pyrano[3,2-c]pyridinyl-g-pyranone scaffold,were characterized from the ascidian-derived fungus Amphichorda felina SYSU-MS7908.Their structures were elucidated by spectroscopic methods,X-ray diffraction and electronic circular dichroism(ECD)calculations.A plausible biosynthetic pathway was proposed.The isolated compounds displayed moderate inhibitory activity against acetylcholinesterase with 50%inhibiting concentration(IC_(50))values of 18.8-53.2 mmol/L.
