Monoclinicα-MoP_(2),with the OsGe2-type structure(space group C2/m,Z=4)and lattice parameters a=8.7248(11)Å,b=3.2322(4)Å,c=7.4724(9)Å,andβ=119.263°,was synthesized under a pressure of 4~GPa at a ...Monoclinicα-MoP_(2),with the OsGe2-type structure(space group C2/m,Z=4)and lattice parameters a=8.7248(11)Å,b=3.2322(4)Å,c=7.4724(9)Å,andβ=119.263°,was synthesized under a pressure of 4~GPa at a temperature between 1100℃and 1200℃.The structure ofα-MoP_(2) and its relationship to other transition metal diphosphides are discussed.Surprisingly,the ambient pressure phase orthorhombicβ-MoP_(2)(space group Cmc21)is denser in structure thanα-MoP_(2).Room-temperature high-pressure x-ray diffraction studies exclude the possibility of phase transition fromβ-MoP_(2) to α-MoP_(2),suggesting thatα-MoP_(2) is a stable phase at ambient conditions;this is also supported by the total energy and phonon calculations.展开更多
The van der Waals(vdW)MnSb4Te7is a newly synthesized antiferromagnetic(AFM)topological insulator hosting a robust axion insulator state irrelative to the specific spin structure.However,the intrinsic hole doped charac...The van der Waals(vdW)MnSb4Te7is a newly synthesized antiferromagnetic(AFM)topological insulator hosting a robust axion insulator state irrelative to the specific spin structure.However,the intrinsic hole doped character of MnSb_4Te_7makes the Fermi level far away from the Dirac point of about 180 meV,which is unfavorable for the exploration of exotic topological properties such as the quantum anomalous Hall effect(QAHE).To shift up the Fermi level close to the Dirac point,the strategy of partially replacing Sb with Bi as Mn(Sb_(1-x)Bi_(x))_(4)Te_(7)was tried and the magnetotransport properties,in particular,the anomalous Hall effect,were measured and analyzed.Through the electron doping,the anomalous Hall conductanceσAH changes from negative to positive between x=0.3 and 0.5,indicative of a possible topological transition.Besides,a charge neutrality point(CNP)also appears between x=0.6 and 0.7.The results would be instructive for further understanding the interplay between nontrivial topological states and the magnetism,as well as for the exploration of exotic topological properties.展开更多
目的探讨妊娠期肝内胆汁淤积症(intrahepatic cholestasis of pregnancy,ICP)患者细胞炎症相关因子与肝功能的关系及其对妊娠结局的影响方法采用回顾性临床研究,选取2014-01/2016-10确诊为孕晚期ICP患者72例为研究对象,其中,符合轻度ICP...目的探讨妊娠期肝内胆汁淤积症(intrahepatic cholestasis of pregnancy,ICP)患者细胞炎症相关因子与肝功能的关系及其对妊娠结局的影响方法采用回顾性临床研究,选取2014-01/2016-10确诊为孕晚期ICP患者72例为研究对象,其中,符合轻度ICP者40例(轻度组),符合重度ICP者32例(重度组),另选取同期90例正常妊娠无并发症孕晚期孕妇为对照组,留取禁食后血清总胆汁酸(total bile acids,TBA)、谷草转氨酶(aspartate transaminase,AST)、谷丙转氨酶(alanine transaminase,ALT)、白介素(interleukin,IL)-6、IL-10、IL-12和肿瘤坏死因子-α(tumor necrosis factorα,TNF-α)标本后送检.采用ELISA法测定两组血清IL-6、IL-10、IL-12和TNF-α水平,应用全自动生化分析仪测定肝功能指标.结果ICP组患者血清IL-6、IL-10、IL-12、TNF-α、TBA、ALT、AST水平显著高于对照组,差异有统计学意义(P<0.05);ICP重度组患者血清IL-6、IL-10、IL-12、TNF-α、TBA、ALT、AST水平高于轻度组,差异有统计学意义(P<0.05),经Pearson相关因素分析显示,IL-6、IL-10、IL-12、TNF-α与TBA、ALT、AST水平均呈正相关(P<0.05).结论妊娠期肝内胆汁淤积症患者炎症细胞因子水平影响患者的肝功能,肝功能指标及细胞炎症因子对预测不良妊娠结局具有积极的作用.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant Nos.92065201,11874264,and 11974154)the Starting Grant of ShanghaiTech University and Analytical Instrumentation Center,SPST,ShanghaiTech University (Grant No.SPST-AIC10112914)support from the Natural Science Foundation of Shandong Province,China (Grant No.ZR2022MA004)。
文摘Monoclinicα-MoP_(2),with the OsGe2-type structure(space group C2/m,Z=4)and lattice parameters a=8.7248(11)Å,b=3.2322(4)Å,c=7.4724(9)Å,andβ=119.263°,was synthesized under a pressure of 4~GPa at a temperature between 1100℃and 1200℃.The structure ofα-MoP_(2) and its relationship to other transition metal diphosphides are discussed.Surprisingly,the ambient pressure phase orthorhombicβ-MoP_(2)(space group Cmc21)is denser in structure thanα-MoP_(2).Room-temperature high-pressure x-ray diffraction studies exclude the possibility of phase transition fromβ-MoP_(2) to α-MoP_(2),suggesting thatα-MoP_(2) is a stable phase at ambient conditions;this is also supported by the total energy and phonon calculations.
基金the Shanghai Science and Technology Innovation Action Plan(Grant No.21JC1402000)the National Natural Science Foundation of China(Grant No.12004405)+3 种基金the State Key Laboratory of Functional Materials for Informatics(Grant No.SKL2022)the Double FirstClass Initiative Fund of ShanghaiTech University,the Analytical Instrumentation Center(Grant No.SPST-AIC10112914)SPST,and ShanghaiTech Universitythe State Key Laboratory of Surface Physics and Department of Physics of Fudan University(Grant No.KF2022_13)。
文摘The van der Waals(vdW)MnSb4Te7is a newly synthesized antiferromagnetic(AFM)topological insulator hosting a robust axion insulator state irrelative to the specific spin structure.However,the intrinsic hole doped character of MnSb_4Te_7makes the Fermi level far away from the Dirac point of about 180 meV,which is unfavorable for the exploration of exotic topological properties such as the quantum anomalous Hall effect(QAHE).To shift up the Fermi level close to the Dirac point,the strategy of partially replacing Sb with Bi as Mn(Sb_(1-x)Bi_(x))_(4)Te_(7)was tried and the magnetotransport properties,in particular,the anomalous Hall effect,were measured and analyzed.Through the electron doping,the anomalous Hall conductanceσAH changes from negative to positive between x=0.3 and 0.5,indicative of a possible topological transition.Besides,a charge neutrality point(CNP)also appears between x=0.6 and 0.7.The results would be instructive for further understanding the interplay between nontrivial topological states and the magnetism,as well as for the exploration of exotic topological properties.
文摘目的探讨妊娠期肝内胆汁淤积症(intrahepatic cholestasis of pregnancy,ICP)患者细胞炎症相关因子与肝功能的关系及其对妊娠结局的影响方法采用回顾性临床研究,选取2014-01/2016-10确诊为孕晚期ICP患者72例为研究对象,其中,符合轻度ICP者40例(轻度组),符合重度ICP者32例(重度组),另选取同期90例正常妊娠无并发症孕晚期孕妇为对照组,留取禁食后血清总胆汁酸(total bile acids,TBA)、谷草转氨酶(aspartate transaminase,AST)、谷丙转氨酶(alanine transaminase,ALT)、白介素(interleukin,IL)-6、IL-10、IL-12和肿瘤坏死因子-α(tumor necrosis factorα,TNF-α)标本后送检.采用ELISA法测定两组血清IL-6、IL-10、IL-12和TNF-α水平,应用全自动生化分析仪测定肝功能指标.结果ICP组患者血清IL-6、IL-10、IL-12、TNF-α、TBA、ALT、AST水平显著高于对照组,差异有统计学意义(P<0.05);ICP重度组患者血清IL-6、IL-10、IL-12、TNF-α、TBA、ALT、AST水平高于轻度组,差异有统计学意义(P<0.05),经Pearson相关因素分析显示,IL-6、IL-10、IL-12、TNF-α与TBA、ALT、AST水平均呈正相关(P<0.05).结论妊娠期肝内胆汁淤积症患者炎症细胞因子水平影响患者的肝功能,肝功能指标及细胞炎症因子对预测不良妊娠结局具有积极的作用.
