Background The relationship between inflammatory markers and the characteristics of coronary atherosclerosis plaques is uncertain. The aim of the present study was to evaluate the relationship between the characterist...Background The relationship between inflammatory markers and the characteristics of coronary atherosclerosis plaques is uncertain. The aim of the present study was to evaluate the relationship between the characteristics of coronary atherosclerosis plaques and inflammatory markers such as high sensitivity C-reactive proteins （Hs-CRP） and interleukin-6 （IL-6）. Methods All patients suspected of having coronary heart disease （CHD） underwent Siemens 64-slice CT angiography （64-SCTA） to distinguish the quality of plaque of coronary artery lesions. Blood samples were taken to measure levels of serum Hs-CRP and IL-6 in different plaque groups and the control group and compared with the value of 64-SCTA for detection of coronary artery plaque. Results The sensitivity of detecting coronary artery plaque by 64-SCTA was 87.4%, the specificity was 87.1%, the positive predictive value was 82.2%, and the negative predictive value was 91.0%. Comparing the levels of serum Hs-CRP and IL-6 among plaque groups, the mean levels of serum Hs-CRP and IL-6 in three plaque groups were significantly higher than those in the control group （P 〈0.01）. The mean levels of serum Hs-CRP and IL-6 in the soft plaque group and mixed plaque group were significantly higher than those in hard plaque group （P〈0.01）. Plaque burden in the soft plaque group and mixed plaque group was significantly higher than in the hard plaque group （P 〈0.01）, but there was no statistical difference between the soft plaque group and mixed plaque group （P=-0.246）. There was a negative correlation between the CT scale and Hs-CRP and IL-6 levels in the soft plaque group （r= -0.621, P〈0.01, and r= -0.593, P 〈0.01 respectively）. There was a positive correlation between the plaque burden and Hs-CRP and IL-6 levels in the soft plaque group （r=0.579, P〈0.05 and r=0.429, P〈0.05 respectively）. Conclusions 64-SCTA is an effective way to distinguish the different quality of coronary atherosclerosis plaque. Serum Hs-CRP and IL-6 l展开更多
[目的]明确29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂对玉米田一年生杂草的防效及对玉米的安全性。[方法]采用随机区组试验设计方法进行田间药效试验。[结果] 29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂在用量为261...[目的]明确29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂对玉米田一年生杂草的防效及对玉米的安全性。[方法]采用随机区组试验设计方法进行田间药效试验。[结果] 29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂在用量为261、304.5、348 g a.i./hm2的条件下,施药后30 d对玉米田一年生杂草的鲜重防效为88.64%、91.60%、95.26%,防效较好,玉米的增产率分别为9.37%、10.17%、11.32%。其中,在304.5 g a.i./hm2剂量下,防效与增产率要优于3个对照药剂。[结论] 29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂在试验剂量下,于玉米田苗后、杂草2～4叶期进行茎叶喷雾处理,对玉米安全,无药害发生,除草效果良好,并具有一定的增产作用,可以作为玉米田的主要除草剂进行使用。展开更多
文摘Background The relationship between inflammatory markers and the characteristics of coronary atherosclerosis plaques is uncertain. The aim of the present study was to evaluate the relationship between the characteristics of coronary atherosclerosis plaques and inflammatory markers such as high sensitivity C-reactive proteins （Hs-CRP） and interleukin-6 （IL-6）. Methods All patients suspected of having coronary heart disease （CHD） underwent Siemens 64-slice CT angiography （64-SCTA） to distinguish the quality of plaque of coronary artery lesions. Blood samples were taken to measure levels of serum Hs-CRP and IL-6 in different plaque groups and the control group and compared with the value of 64-SCTA for detection of coronary artery plaque. Results The sensitivity of detecting coronary artery plaque by 64-SCTA was 87.4%, the specificity was 87.1%, the positive predictive value was 82.2%, and the negative predictive value was 91.0%. Comparing the levels of serum Hs-CRP and IL-6 among plaque groups, the mean levels of serum Hs-CRP and IL-6 in three plaque groups were significantly higher than those in the control group （P 〈0.01）. The mean levels of serum Hs-CRP and IL-6 in the soft plaque group and mixed plaque group were significantly higher than those in hard plaque group （P〈0.01）. Plaque burden in the soft plaque group and mixed plaque group was significantly higher than in the hard plaque group （P 〈0.01）, but there was no statistical difference between the soft plaque group and mixed plaque group （P=-0.246）. There was a negative correlation between the CT scale and Hs-CRP and IL-6 levels in the soft plaque group （r= -0.621, P〈0.01, and r= -0.593, P 〈0.01 respectively）. There was a positive correlation between the plaque burden and Hs-CRP and IL-6 levels in the soft plaque group （r=0.579, P〈0.05 and r=0.429, P〈0.05 respectively）. Conclusions 64-SCTA is an effective way to distinguish the different quality of coronary atherosclerosis plaque. Serum Hs-CRP and IL-6 l
文摘[目的]明确29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂对玉米田一年生杂草的防效及对玉米的安全性。[方法]采用随机区组试验设计方法进行田间药效试验。[结果] 29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂在用量为261、304.5、348 g a.i./hm2的条件下,施药后30 d对玉米田一年生杂草的鲜重防效为88.64%、91.60%、95.26%,防效较好,玉米的增产率分别为9.37%、10.17%、11.32%。其中,在304.5 g a.i./hm2剂量下,防效与增产率要优于3个对照药剂。[结论] 29%环磺酮·烟嘧磺隆·莠去津可分散油悬浮剂在试验剂量下,于玉米田苗后、杂草2～4叶期进行茎叶喷雾处理,对玉米安全,无药害发生,除草效果良好,并具有一定的增产作用,可以作为玉米田的主要除草剂进行使用。
