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基于“活血化瘀法”探讨三七注射液在慢性肾病中的作用研究进展

Research Progress on the Role of Sanqi Injection in Chronic Kidney Disease Based on the Method of Promoting Blood Circulation and Removing Blood Stasis
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摘要 慢性肾病(chronic kidney disease, CKD)是一种由各种原因引起的肾脏病理改变和功能损伤的进行性疾病。三七注射液是由中药三七提取的活血化瘀类中药制剂,其成分包括人参皂甙和三七皂苷,具有抗炎、抗氧化、抗纤维化、改善血液循环等药理作用。关于三七注射液干预CKD的临床研究中也显示出了治疗潜力。本文基于“活血化瘀法”从慢性肾衰竭、糖尿病肾病、系统性红斑狼疮肾炎等方面的作用研究进展探讨三七注射液的干预作用,提出当前研究的不足和改进意见,为进一步临床应用与实验研究提供有力支撑和有益思路。 Chronic kidney disease (CKD) is a progressive disease caused by various pathological changes and functional impairments in the kidney. Sanqi injection is extracted from the traditional Chinese medicine Sanqi, and its components include ginsenosides and Sanqi saponins. It has pharmacologi-cal effects such as anti-inflammatory, antioxidant, anti fibrosis, and improving blood circulation. Clinical studies on the intervention of Sanqi injection in CKD have also shown therapeutic potential. This article discusses the intervention effect of Sanqi injection from the research progress of chronic renal failure, diabetes nephropathy, systemic lupus erythematosus nephritis and other aspects, and provides support and ideas for further clinical application and experimental research.
出处 《中医学》 2024年第3期425-432,共8页 Traditional Chinese Medicine
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