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高血压合并睡眠呼吸暂停低通气综合征与动脉硬化的研究进展

Research Progress of Hypertension Combined with Obstructive Sleep Apnea-Hypopnea Syndrome and Arteriosclerosis
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摘要 阻塞性睡眠呼吸暂停低通气综合征(OSAHS)为一种常见的睡眠呼吸障碍性疾病,与高血压、心血管疾病等密切相关。高血压合并OSAHS患者表现出特异的血压特点,二者合并会加剧心血管动脉硬化不良事件的发生和死亡风险。动脉硬化是心血管疾病的重要病理基础,动态动脉硬化指数(AASl)及血浆致动脉硬化指数(AIP)是近年提出的评价动脉硬化度的新型敏感指标,对于早期识别高血压合并OSAHS发生动脉硬化的高危人群,行危险分层和及时防治具有显著的临床意义。本文就高血压合并OSAHS与动脉硬化的研究进展予以综述。 Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common sleep breathing disorder, which is closely related to hypertension and cardiovascular diseases. Patients with hypertension com-bined with OSAHS show specific blood pressure characteristics, and the combination of the two will increase the occurrence of adverse events and death risk of cardiovascular arteriosclerosis. Arteri-osclerosis is an important pathological basis of cardiovascular diseases. Ambulatory arterial stiff-ness index (AASl) and Atherogenic index of plasma (AIP) are new sensitive indexes proposed in re-cent years to evaluate the degree of arteriosclerosis, which have significant clinical significance for early identification of high-risk groups of arteriosclerosis caused by hypertension combined with OSAHS, risk stratification and timely prevention and treatment. This article reviews the research progress of hypertension complicated with OSAHS and arteriosclerosis.
出处 《临床医学进展》 2024年第2期3175-3180,共6页 Advances in Clinical Medicine
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