摘要
卵巢癌是全球女性癌症相关死亡的第八大原因,严重威胁着全球女性的生命和健康。目前,卵巢癌的早期筛查、治疗及预后监测方面仍有较大的研究空间。肿瘤微环境中与肿瘤相关的各种炎症指标可能是癌症发生和进展的关键因素。基于全血细胞计数的复合炎症标志物,即SII、PLR、NLR、LMR等,不仅在多种癌症中得到广泛研究,而且与OC的发生、发展具有相关性。本文综述SII、PLR、NLR及LMR在卵巢癌的诊断及预后评估中的研究进展,以期对未来临床实践提供帮助。
Ovarian cancer (OC) is the eighth leading cause of female cancer-related deaths in worldwide, which seriously threatens the life and health of women all over the world. At present, there is still a large research space in the early screening, treatment and prognosis monitoring of ovarian cancer. Vari-ous markers of inflammation associated with tumors in the tumor micro environment may be key factors in the development and progression of cancer. Complex inflammatory markers based on complete blood count, namely SII, PRL, NLR, LMR, etc., which not only been widely studied in a vari-ety of cancers, but also have a correlation with the occurrence and development of OC. This article reviews the research progress of SII, PLR, NLR and LMR in the diagnosis and prognosis estimation of ovarian cancer, in order to provide help for future clinical practice.
出处
《临床医学进展》
2023年第11期17362-17373,共12页
Advances in Clinical Medicine
