摘要
幽门螺杆菌(Helicobacter pylori, Hp)是一种世界上感染最普遍的病原体之一,据最新研究报道,Hp不仅与大部分胃肠相关疾病有密切的关系,甚至跟胃肠外其他系统疾病也有一定的相关性。有研究表明,幽门螺杆菌感染可以经过脑–肠轴(Brain-gut axis, BGA)刺激神经递质及激素释放,从而影响神经调节、内分泌和免疫反应,进而影响患者的思维和心理活动,目前已有研究证实幽门螺杆菌感染是阿尔兹海默症(AD)的危险因素。本文将针对于Hp感染的各项影响因素,尤其是其与焦虑抑郁状态相关性研究及治疗做一综述。
Helicobacter pylori (H. pylori) is one of the most commonly infected pathogens in the world, accord-ing to the latest research report, H. pylori not only had a close relationship with gastric disease, but it also had a certain correlation with other gastrointestinal system diseases. Research has shown that, H. pylori infection can stimulate the release of neurotransmitters and hormones through the Brain-gut axis (BGA), thus affecting neuromodulation, endocrine and immune responses, which af-fects the thinking and psychological activities of patients. Currently, research has confirmed that H. pylori infection is a risk factor for Alzheimer’s disease (AD). This article will review the various in-fluencing factors of H. pylori infection, especially its correlation with Anxiety-Depression condition, as well as its treatment.
出处
《临床医学进展》
2023年第8期13671-13676,共6页
Advances in Clinical Medicine
