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胶体金试纸条快速检测结核抗体的临床意义探讨 被引量:12

The clinical significance of measuring serum anti-mycobacterium tuberculosis antibody by colloidal gold strip rapid test
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摘要 目的 评价胶体金试纸条结核抗体快速检测法在结核病临床诊断中的意义。方法 以临床诊断为参考标准 ,以敏感性、特异性和准确性作为评价指标 ,评价该方法在结核病临床诊断中的价值。结果 胶体金试纸条结核抗体快速检测法诊断结核病的敏感性为 77.2 7% ,特异性为87.78% ,可靠性为 82 .5 8%。结论 胶体金试纸条结核抗体快速检测法测定血清结核抗体 。 Objective To evaluate the significance of measuring serum anti mycobacterium tuberculosis antibody by colloidal gold strip rapid test.Methods Serum anti mycobacterium tuberculosis antibody was measured by colloidal gold strip rapid test method,with clinical diagnosis as reference standard to calculate the sensitivity,the specificity and the reliability of the strip rapid test method.Results The sensitivity of the strip rapid test method was 77.27%,while the specificity was 87.78%,the reliability 82.58 %.Conclusion Detection of the tuberculosis antibody by colloidal gold strip rapid test method is helpful for diagnosing tuberculosis and can be used to assist the diagnosis of mycobacterium tuberculosis.
出处 《国外医学(临床生物化学与检验学分册)》 2004年第3期209-210,共2页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
关键词 胶体金 试纸条 结核抗体 结核杆菌 预防措施 tuberculosis antibody,bacterial gold colloid reagent strips
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  • 1Noordhoek GT,van-Embden JD,Kolk AH.Reliability of nucleic acid amplification for detection of Mycobacterium tuberculosis:an international collaborative quality control study among 30 laboratories.J Clin Microbiol,1996,34(10):2522-2525. 被引量:1
  • 2Manca C,Lyashchenko K,Wiker HG,et al.Molecular cloning,purification,and serological characterization of MPT63,a novel antigen secreted by Mycobacterium tuberculosis.Infect Immun,1997,65(1):16-23. 被引量:1
  • 3Laqueyrerie A,Militzer P,Romain F,et al.Cloning,sequencing,and expression of the apa gene coding for the Mycobacterium tuberculosis 45/47-kilodalton secreted antigen complex.Infect Immun,1995,63(10):4003-4010. 被引量:1

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