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小剂量甲状腺素治疗能减少Graves病的复发吗? 被引量:3

Can low dose thyroxine reduce recurrence of Graves′ disease?
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摘要 观察单用抗甲状腺药物 (ATD)治疗组与ATD联合小剂量甲状腺素治疗组之间Graves病(GD)复发率。结果显示两组治疗结束时临床表现、甲状腺功能、TSH受体抗体 (TRAb)阳性率均相似 ,停药 1年GD复发率差异无显著性 ,但复发者甲状腺肿较严重、突眼率较高以及TRAb阳性率较高 (均P <0 .0 1)。 Recurrence rate was observed in patients with Graves′ disease (GD) treated by antithyroid drugs only or combined with low-dose thyroxine. The results showed that the clinical manifestations, thyroid function and positive rate of TSH receptor antibody (TRAb) were similar in both groups, so did the recurrence rate 1 year after the with drawal of drugs. The patients who relapsed had more severe goiter, higher ophthalmopathy rate and higher positive rate of TRAb at the end of treatment in 2 groups (all P<0.01).
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2004年第2期122-123,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 小剂量 甲状腺素 治疗 GRAVES病 复发 Graves′ disease Antithyroid agents Thyroxine
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