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靶控输注异丙酚与吸入异氟醚麻醉在腹腔镜胆囊切除术中的效果 被引量:6

Comparison of anaesthesia maintained by propofol target-controlled infusion with isoflurane inhalation for laparoscopic cholecystectomy
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摘要 目的 :比较靶控输注异丙酚 (target controlledinfusion ,TCI)全凭静脉麻醉和异氟醚吸入麻醉两种不同方式在腹腔镜胆囊切除术 (laparoscopiccholecystectomy ,LC)应用中的临床效果。方法 :将 30例择期行LC术的患者随机分为两组。TCI组 (T组 ) (n =1 5 ) :设定诱导时靶浓度为 4 μg/ml,术中维持异丙酚靶浓度为 3~ 3.5 μg/ml。异氟醚组 (I组 ) (n =1 5 ) :采用 3%异氟醚吸入诱导、1 %~ 2 .5 %维持。术中监测心率 (heartrate,HR)、收缩压 (systolicbloodpressure,SBP)、舒张压 (diastolicbloodpressure ,DBP)、平均动脉压 (meanarterialpres sure ,MAP)等指标。结果 :T组诱导时间显著短于I组 (P <0 .0 5 ) ,术中T组生命体征维持相对平稳 ,术后苏醒T组明显优于I组。结论 :TCI全凭静脉麻醉方法用于LC术 ,术中血流动力学稳定 ,术后患者苏醒迅速 。 Objective:To study the benefit of propofol with target controlled infusion(TCI) for laparoscopic cholecystectomy(LC) in comparison with isoflurane inhalation.Methods:Thirty patients scheduled for LC were randomized to two groups:propofol group(T group)(n=15) and isoflurane group(I group)(n=15). The patients in T group were given TCI with the target concentration 4 μg/ml during induction and 3~3.5 μg/ml during maintenance. 3% isoflurane during induction and 1%~2.5% during maintenance were inhaled in I group. SBP,DBP and HR were monitored continuously in two groups during operation.Results:The time of induction in T group was shorter than that in I group(P<0.05). The vital signs were stable in T group during operation. The patients in T group gained more comfortable recovery than those in I group.Conclusion:During the anaesthesia of propofol TCI for LC the hemodynamics is more stable than that of isoflurane inhalation,and the recovery is better. So the anaesthesia maintained by propofol target controlled infusion for laparoscopic cholecystectomy is better than that by isoflurane inhalation.
作者 吴群 韩宇
出处 《肝胆胰外科杂志》 CAS 2004年第2期103-105,共3页 Journal of Hepatopancreatobiliary Surgery
关键词 胆囊切除术 腹腔镜 靶控输注 异丙酚 异氟醚 cholecystectomy,laparoscopic target controlled infusion propofol isoflurane
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