摘要
目的 :研究涎腺腺样囊性癌中层粘连蛋白 (LN)及其受体 (LN -R)表达特征及其与腺样囊性癌的临床病理指标的关系。方法 :用超敏S -P免疫组化方法检测34例涎腺腺样囊性癌LN和LN -R的表达。结果 :LN -R的表达与涎腺腺样囊性癌组织分型、临床分期有关 (P<0.05) ,LN的表达仅与腺样囊性癌的组织分型有关 (P<0.05)。结论 :LN及其受体LN
Objective:To study the expression of laminin and its receptor and its relation to some clinicopathologic characteristics in adenoid cystic carcinoma of the salivary gland.Methods:The expression of laminin and its receptor in34cases was studied by immunohistochemically hypersensitive S_P methods.Result:The expression of laminin receptor was related to the histological typing and clinical stage of adenoid cystic carciˉnoma of the salivary gland(P<0.05).The expression of laminin was only related to the lustologicol typing(P<0.05)but not in relation to the clinical stage(P>0.05)of tumor.Conclusion:It suggests that the expression of laminin and its receptor is considered to be an important indicator of malignancy of adenoid cystic carcinoma.
出处
《天津医药》
CAS
北大核心
2004年第5期265-267,F003,共4页
Tianjin Medical Journal
关键词
层粘连蛋白
受体
涎腺腺样囊性癌
生物学行为
carcinoma,adenoid cystic receptors,laminin laminin immunohistochemistry
