摘要
目的 探讨自固化磷酸钙人工骨 (autosettingcalciumphosphatecement,ACPC)椎体成形术对椎体生物力学性能的影响。方法 自 8具尸体脊柱标本上取胸腰段椎体共 2 4节 ,在前屈压缩下造成骨折 ,随机分成 4组 ,分别经双侧椎弓根注入椎体 2、4、6和 8mLACPC ,再行前屈压缩。测定初始和术后椎体抗压强度和刚度 ,观察实验过程中椎体高度变化。结果 经双侧椎弓根注入椎体 2mLACPC就能显著性增强椎体抗压强度 ,同时刚度无明显变化。实验虽能在一定程度上恢复椎体高度 ,但从临床角度看无重要意义。结论 合理选择灌注剂量既能显著恢复椎体的生物力学性能 ,又可以减少灌注剂渗漏。
Purpose: To discuss the relation between different volume of autosetting calcium phosphate cement (ACPC) during vertebroplasty and postoperative restoration of biomechanical properties and height. Methods: Flexional compression fractures were experimentally created in 24 thoracolumbar vertebral bodies (T10-L 2) obtained from 8 spines harvested from cadavers. After initial strength, stiffness and vertebral height were determined, the vertebral bodies were stabilized using bipedicular injections of ACPC totaling 2, 4, 6, or 8 mL and recompressed, after which postoperative strength, stiffness and vertebral height were measured. Results: Strength was significantly increased when 2 mL ACPC was injected, while stiffness had no obvious change. Although in this experiment vertebral height was restored to a certain degree, it is of no significance as viewed from clinic therapy. Conclusions: Reasonably choosing cement volume can not only significantly restore vertebral biomechanical property but also reduce cement leakage. Vertebroplsty has little effect on height restoration of damaged vertebral body.
出处
《复旦学报（医学版）》
EI
CAS
CSCD
北大核心
2004年第3期263-266,共4页
Fudan University Journal of Medical Sciences
