摘要
目的 探讨抗抑郁剂治疗抑郁亚综合征 (SSD)的疗效与医疗耗资。方法 将 4 0例不愿接受抗抑郁剂治疗仅要求一般对症处理作为A组 ,其它的 81例SSD随机分成B、C两组 ,分别接受丙咪嗪、氟西汀治疗。对三个组治疗前后复发率、婚姻质量以及医疗耗资等方面进行分析 ,并与重症抑郁的治疗结果对照 ,还对服药后疗效差原因进行了分析。结果 接受丙咪嗪、氟西汀治疗的SSD ,经治疗后其婚姻质量较对症处理组的病人有明显提高 ,且复发率与医疗耗资明显下降。与重症抑郁治疗效果对照 ,显示SSD病人接受治疗后起效与症状改善时间均较短。而疗效差的因素除家族中有酒依赖、人格改变外 ,与慢性心因的存在 ,服药的依赖性 ,用药量不足 (小于治疗量 ) ,未及时治疗 (即从疾病开始到治疗超过 6个月 )亦有一定关系 ,B、C两组治疗前后医疗耗资比较表明 ,B、C两组治疗后虽然医疗耗资明显增加 ,但经济收入明显增高 ,误工费显著下降 ,总收入提高。结论 及时、有效地治疗SSD是极其重要的。
Objective To study the curative effect and the treatment cost of treating SSD with antidepressant.Methods 40 SSD patients refusing the treatment of antidepressant,only asked the normal treatment according to the symptom,were referred to as A group,the others as B & C groups at random to receive the treatment of imipramin,fluoxetine,placebo treatment respectively at the same time.Finally,analyzed the reason of the relapse rates,marital quality and economic loss,etc,for the three groups before and after the treatment.Compared with severe depressive patients,also analyzed the reason of poor curative effect before and after the treatment.Results The marital quality of SSD patients who received imipramine,fluoxetine treatment obviously improved,compared with that of A group treated as per the symptom,and the relapse rate and economic loss have evidently decreased.Compared with severe depressive patients,it showed that the effective period after taking drug and the improving period were shorter.All the factors of poor curative effects,besides alcoholic dependence and personality changes,also due to chronic psychological factors ,drug compliance,taking inadequate medicine(less than treatment quantity),delayed treatment(more than 6 months after the occurring of the disease).The treatment cost for B & C groups before and after the treatment shown that although the cost increased obviously after the treatment but the economic income added and the fee of delaying work decreased clearly and the total income raised.Conclusion It is necessary and important that SSD should be treated in time and effectively.
出处
《四川精神卫生》
2004年第1期14-16,共3页
Sichuan Mental Health
