摘要
目的 探讨与不稳定型心绞痛患者早期预后相关的临床因素。方法 对 118例不稳定型心绞痛患者进行Braunwald分级 ,测定cTnI及CK、CK MB水平 ,行冠脉造影、心电图及超声检查 ,记录 4 2d内心脏事件发生情况。结果 发生早期心脏终点事件组患者具备糖尿病病史、有心电图、超声异常改变、多于一支冠脉狭窄的比例明显高于未发生终点事件组 ,同时临床Braunwald分级在Ⅱ、Ⅲ级及CK MB和cTnI阳性的比例也高于对照组。Logistic回归分析结果显示 :糖尿病病史、cTnI阳性、Braunwald分级Ⅱ～Ⅲ级、心电图和超声异常改变以及CK MB阳性对终点事件有较强预测价值。结论 糖尿病病史、cTnI阳性、Braunwald分级、心电图和超声异常改变以及CK MB阳性是不稳定性心绞痛早期预后的有价值的预测因子。
Objective To investigate possible clinical factors related to the early prognosis of unstable angina (UA). Methods A total of 118 UA patients underwent Braunwald classification, coronary angiography, electrocardiogram and echocardiogram examination. Blood specimens were analyzed for cardiac troponin I(cTnI), CK and CK-MB. The information about cardiac events occurrence within 42 days was collected. Results Compared with control group, the subjects suffered from any early cardiac event had much higher rate of diabetes mellitus history and experienced abnormalities of electrocardiogram and echocardiogram as well as multi-branch coronary stenosis( P <0.001). Braunwald classification gradeⅡand Ⅲ, positive cTnI (at least 0.1 ng/ml ) and CK-MB were also well related to poor clinical outcome. Logistic regression analysis demonstrated that diabetes history, cTnI elevation, Braunwald classification gradeⅡand Ⅲ,abnormalities of electrocardiogram and echocardiogram as well as CK-MB elevation could predict the occurrence of cardiac endpoint events. Conclusion Diabetes history, cTnI elevation, Braunwald classification gradeⅡand Ⅲ,abnormalities of electrocardiogram and echocardiogram as well as CK-MB elevation were valuable risk factors related to early prognosis of unstable angina.
出处
《中华老年多器官疾病杂志》
2004年第1期34-36,共3页
Chinese Journal of Multiple Organ Diseases in the Elderly
