摘要
本实验以肉用AA雏鸡和蛋用罗曼雏鸡为实验动物,从细胞免疫和体液免疫首次研究了甲壳素对鸡新城疫疫苗的免疫调节作用,并与油乳剂和蜂胶佐剂加以比较,以观察不同免疫佐剂对鸡新城疫的免疫调节作用。试验结果表明,三种佐剂的疫苗在肉鸡组免疫后5～10d,蛋鸡组免疫后5～15d,甲壳素疫苗组HI抗体效价显著高于其它组;在肉鸡组免疫后15～37d,蛋鸡组免疫后22～50d,油乳剂疫苗组HI抗体效价显著高于其它组。用三种不同佐剂的疫苗免疫后,肉鸡和蛋鸡甲壳素疫苗组的细胞免疫水平显著高于其它组。
The experiments were conducted to study the immune modulation effects of chitin, proplisl and oil to Newcastle disease vaccines by ways of cellular and humoral immunity. The results of the experiments were as follows: the effects on humoral immunity in ND-vaccinated AA chicken at 10,15 days and Roman chicken at 10, 20 days, the ND HI antibody titers of chitin group of chicken showed significant differences from others; oil group of immunized AA chicken was significantly higher than others at 20,27,35,42 days; oil group of immunized Roman chicken was significantly higher than others at 27,35,42,56 days, respectively. T lymphocyte proliferative responses of chitin group was significantly higher than others after immunity.
出处
《中国预防兽医学报》
CAS
CSCD
北大核心
2004年第2期136-138,共3页
Chinese Journal of Preventive Veterinary Medicine
关键词
甲壳素
细胞免疫
鸡新城疫HI抗体效价
chitin
immune modulation
HI antibody titer against NDV in chicken
