摘要
目的探究妊娠中、晚期胎儿超声异常与染色体异常关系及其妊娠结局研究。方法随机选取2016年11月-2017年11月的96例在我院治疗的妊娠中期、晚期超声异常的孕妇,取妊娠期中期以及妊娠晚期的患者进行脐血的抽取,随后进行然是人体的检查,观察并记录被检查者的情况。结果超声软指标异常2项异常、3项及以上异常发生出现染色体异常以及染色体三体的概率要明显高于单项异常(P<0.05),羊水过多组的染色体异常的检出率要明显高于羊水正常组的检出率(P<0.05),胎儿超声异常情况与染色体异常存在密切联系。结论在临床诊断中,妊娠中期以及妊娠晚期的胎儿出现超声异常、羊水过多以及超声软指标异常的现象后,胎儿的染色体异常的发生率要明显升高,因此对于胎儿的染色体检查需要进行脐血管的穿刺。
Objective:To explore the relationship between abnormal ultrasonography and chromosome abnormality in fetuses in middle and late pregnancy and its pregnancy outcome.Methods:A total of 96 pregnant women who were treated with abnormal ultrasonography during the second and third trimesters from November 2016 to November 2017 were randomly selected,and patients in the second and third trimesters were selected for cord blood extraction,followed by human body examinations,to observe and record the examinees.Results:The ultrasonic soft data anomalies in item 2,3 and above exception occurs the probability of abnormal chromosome and chromosome three body to be significantly higher than the single exception group(P<0.05),hydramnios chromosome abnormality rate of detection rate significantly higher than in normal amniotic fluid group(P<0.05),abnormal fetal ultrasound is closely linked with chromosomal abnormalities.Conclusion:In clinical diagnosis,the incidence of fetal chromosomal abnormality is significantly increased after the abnormal ultrasonography,excessive amniotic fluid and abnormal ultrasound soft indicators in the second and third trimesters of fetuses.Therefore,the umbilical cord puncture is necessary for the chromosome examination of fetuses.
作者
陈志美
杜珍
王定珺
CHEN Zhi-mei;DU Zhen;WANG Ding-jun(The Second People's Hospital of Hainan Province,Hainan Wuzhishan 572299)
出处
《中国优生与遗传杂志》
2019年第9期1076-1078,共3页
Chinese Journal of Birth Health & Heredity
关键词
妊娠中期
妊娠晚期
胎儿超声异常
染色体异常
妊娠结局
Middle term of pregnancy
Late pregnancy
Abnormal fetal ultrasonography
Chromosomal abnormalities
Pregnancy outcomes
